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EN
Plant enzymes are able to catalyse regio- and stereospecific reactions and can be applied to the production of pharmaceutically important compounds.This paper summarizes the results of such biotransformations in freely suspended cells.The factors affecting bioconversion capabilities of cells are also discussed.Special attention is paid to permeabilization and the problems of poorly water-soluble precursors.
EN
for plant cell culture was improved. Diameter of the upper part of the bioreactor, was expanded from 155 to 220 mm. Function of a draughtube was changed from a suspension riser to a downcomer. Instead of original aeration tube with holes stainless steel sintered air sparger was introduced. As a result the aeration rate was reduced sixfold for the same kLa value, and the culture foaming and cell deposit on the bioreactor wall was markedly limited.
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