Nelson’s syndrome is a rare condition of enlarging pituitary mass lesion producing ACTH that can develop after total bilateral adrenalectomy (TBA) in patients with Cushing’s disease. It is characterized by hyperpigmentation of the skin and mucous membranes and elevated plasma levels of ACTH. In this clinical review, the diagnosis and treatment strategies of patients with Nelson’s syndrome including surgery, radiation, and pharmacotherapy are presented.
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.