A colorimetric assay has been developed for studies on neutral red (NR) pinocytosis by small numbers of adherent cells cultured in 96 well plates. The NR uptake per cell mass was much higher in the sea urchin perivisceral adherent cells and human HL-60 cell line monolayers than in the nurine and Atlantic salmon macrophages. The apparent difference points to the usefulness of this novel assay in comparative studies.
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