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Biological properties of lipoic acid

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Bilska A., Wlodek L.
Postępy Higieny i Medycyny Doświadczalnej
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2002
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vol. 56
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issue 2
201-219
EN
Lipoic acid is a prostetic group of H-protein of the glycine cleavage system and the dihydrolipoamide acyltransferases (E2) of the pyruvate, alpha-ketoglutarate and branched-chain alpha-keto acid dehydrogenase complexes. Lipoic acid and its reduced form, dihydrolipoic acid, reacts with oxygen reactive species. This paper reviews the beneficial effects in oxidative stress models or clinical conditions.
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