Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl
Preferences help
Polish version English version Language
enabled [disable] Abstract
Number of results

Results found: 4

Number of results on page
first rewind previous Page / 1 next fast forward last

Search results

Search:
in the keywords:  Ki-67
help Sort By:

help Limit search:
first rewind previous Page / 1 next fast forward last
1
Content available remote

FDG-PET-CT in the early response evaluation for primary systemic therapy of breast cancer

100%
Tőkés T., Torgyík L., Kulka J., Borka K., Szász A., Tóth A., Harsányi L., Lengyel Z., Györke T., Dank M.
Open Medicine
|
2014
|
vol. 9
|
issue 2
306-312
EN
Primary systemic therapy (PST) is a standard treatment for patients with locally advanced breast cancer. We report one of our patients to demonstrate the optimal use of FDG-PET-CT in the routine clinical workup during PST, especially when clinicians face contradictory clinical and pathological findings, and to show the advantages of this imaging modality in the decision-making process about the initial treatment choice. By reviewing the literature we would also like to confirm that FDG-PET-CT is highly sensitive in the measurement of the early therapeutic response and the prediction of the complete pathological remission, as early as after the first cycle of chemotherapy is administered.
2
Content available remote

Apoptotic factors in physiological and pathological processes of teeth and periodontal tissues – literature review

86%
Orzedala-Koszel U., Rahnama M., Lobacz M., Koszel H.
Current Issues in Pharmacy and Medical Sciences
|
2014
|
vol. 27
|
issue 4
229-233
EN
Apoptosis is a physiological process that occurs in the human body throughout the entire life span. This process can be seen in the tissues of the stomatognathic system. A disorder in such programmed cell death processes leads to the development of pathological lesions. Among these are inflammation, osteolytic lesions and neoplastic hyperplasia. We put forward that future studies should concentrate on how to use the knowledge of apoptotic processes and their inhibitors in therapeutic processes involving the stomatognathic system.
3
Publication available in full text mode
Content available

The effect of budesonide on the expression of Ki-67 and PCNA and the apoptotic indexin dogs with inflammatory bowel disease

86%
Szweda M., Rychlik A., Nowicki M., Kaczmar E.
Polish Journal of Veterinary Sciences
|
2017
|
issue 4
4
Content available remote

Metastatic Phenotype of Disseminated Nodal Tumor Cells in Esophageal Cancer

72%
Rehders A., Hosch S., Stoecklein N., Scheunemann P., Peiper M., Knoefel W.
Polish Journal of Surgery
|
2007
|
vol. 79
|
issue 3
173-181
EN
The prognostic relevance of disseminated nodal tumor cells has been demonstrated by several groups. However, their biological behaviour still remains unclear.The aim of the study. Analyse the phenotypic characteristics of disseminated tumor cells in lymph nodes.Material and methods. We established an immuno-enzymatic immuno-gold double-staining technique to simultaneously identify an epithelial antigen as well as the co-expression of plakoglobin, HLA class-I, ICAM-I and Ki-67 on isolated tumor cells. Epithelial cells were marked by the monoclonal antibody Ber-EP4. These results were compared with the corresponding primary tumors.Results. Loss of HLA class-I expression on Ber-EP4+ cells was observed in 33.3% of the patients. ICAM-I neo-expression was detected in 46%, whereas 54% of the cases were ICAM-1 negative. Plakoglobin was expressed in 16% while Ki-67 was detectable only in 5% of the patients. Comparison with the corresponding primary tumors revealed phenotypic alterations of the disseminated cells. In 20% of the cases HLA class-I down-regulation was found, while in 38% plakoglobin was not detectable. In contrast to the primary tumors with a proliferation index of 39%, the nodal Ber-EP4+ cells appeared to be Ki-67 negative in 95% of the patients.Conclusions. Our phenotypic analysis demonstrates that Ber-EP4+ cells in lymph nodes not only display characteristics typical of malignant cells but also phenotypic alterations, in comparison with primary tumors. This is indicative of a selective process which might result in adapted metastatic phenotypes.
first rewind previous Page / 1 next fast forward last
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.