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Mapping of the influenza A hemagglutinin serotypes evolution by the ISSCOR method

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Radomski J., Słonimski P., Zagórski-Ostoja W., Borowicz P.
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2014
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vol. 61
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issue 3
441-451
EN
Analyses and visualizations by the ISSCOR method of influenza virus hemagglutinin genes of different A-subtypes revealed some rather striking temporal relationships between groups of individual gene subsets. Based on these findings we consider application of the ISSCOR-PCA method for analyses of large sets of homologous genes to be a worthwhile addition to a toolbox of genomics - allowing for a rapid diagnostics of trends, and ultimately even aiding an early warning of newly emerging epidemiological threats.
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