Search results

Search:
in the keywords: Head and neck

Sort By:

Limit search:

Synovial sarcoma of carotid space

100%

Krstic V., Milosavljevic M., Mitrovic S., Azanjac G., Knezevic M., Konstantinovic V., Nedovic J.

Open Medicine

2012

vol. 7

issue 4

497-502

Synovial sarcomas are malignant tumors of mesenchymal origin, extremely rarely located in the area of the head and neck. Histologically they can be monophasic, biphasic or poorly differentiated with numerous differential diagnostic dilemmas. A 54-year-old male with synovial sarcoma of the carotid space is presented. The patient refused suggested postoperative radiotherapy and, nine months after the primary surgery, local relapse was verified. Following surgical resection of the local relapse, postoperative radiotherapy treatment was utilized. Ten months after the second surgery, secondary deposits in the lungs were radiographically confirmed, and local recurrence was noticed again. Treatment was continued with symptomatic therapy and eleven months later patient died. Synovial sarcomas of the carotid space are extremely rare, with complex surgical approaches and pathohistological differential diagnostic dilemmas. Diagnosis requires determination of the immunophenotype of the tumor cells, whereas therapy requires an aggressive surgical approach and postoperative radiotherapy.

Quality assurance and dosimetric analysis of intensity modulation radiotherapy using compensators for head and neck cancers

88%

Tyagi A., Nangia S., Chufal K., Mishra M., Ghosh D., Supe S., Singh M.

Polish Journal of Medical Physics And Engineering

2009

vol. 15

issue 4

193-208

In this study we describe our experience in implementing compensator based intensity modulated radiotherapy (cIMRT) for head and neck cancer with regard to pre treatment quality assurance (QA), dosimetric parameters and other technical detail.This study represents the analysis of initial 48 patients who underwent cIMRT for head and neck cancers. All patients were treated with pre treatment QA in terms of point dose with ion chamber and spatial dose comparison with film dosimetry.In our study for all 48 patients, compensators revealed a deviation in central axis dose of 2% ± 1.8% in terms of cumulative calculated versus measured dose. Target coverage for high dose volume (70 Gy) was adequate in terms of volume receiving 93% and 95% of the prescription dose, which was 98.5% and 97.5% respectively. Parotid and other critical organs were spared adequately. Contralateral parotid (CLP) was spared. V30 Gy and V35 Gy was 55.9% and 36.8% for CLP and average dose was 31.7 Gy. Median variation in cumulative measured dose versus cumulative calculated dose was 1.8% (SD + 1.8) and mean variation was 2.5% (95%CI 1.5, 2.6). Range was 0 to 7%.cIMRT is practically feasible. Our QA tests revealed high degree of concordance between cumulative measured doses versus cumulative calculated doses. All dosimetric parameters were within acceptable limits. The manufacturing of compensator is cumbersome but it is a one time job followed by easy treatment delivery and simple QA procedure, high monitor unit (MU) efficiency and less treatment time. cIMRT is easy to implement and now can be applied to larger number of patients with different type of tumor.

Refine search results

1 Open Medicine

1 Polish Journal of Medical Physics And Engineering

1 2012

1 2009

1 Azanjac G.

1 Chufal K.

1 Ghosh D.

1 Knezevic M.

1 Konstantinovic V.

1 Krstic V.

1 Milosavljevic M.

1 Mishra M.

1 Mitrovic S.

1 Nangia S.

1 Nedovic J.

1 Singh M.

1 Supe S.

1 Tyagi A.

Search results

Synovial sarcoma of carotid space

Quality assurance and dosimetric analysis of intensity modulation radiotherapy using compensators for head and neck cancers