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HEALTH-RELATED QUALITY OF LIFE OF A PATIENT FOLLOWING NEUROSURGERY ON GLIOBLASTOMA MULTIFORME (GBM)

100%

Morga R., Moskała M., Adamek D., Góral-Półrola J., Herman-Sucharska I., Pąchalska M.

Acta Neuropsychologica

2018

vol. 16(3)

307-319

Health-related quality of life (HRQoL) plays a role as a patient-centered meaningful endpoint, assessing the direct clinical benefit for a patient. The inclusion of HRQoL measurements in a glioma patient may provide important data to inform clinicians on treatment decision-making. The aim of the study was to evaluate cognitive decline and HRQoL in the clinical care of a patient following neurosurgery on of glioblastoma multiforme (GBM). A 69-year-old female developed malignant brain glioma in the right temporal-occipital area; this being confirmed by CT and MR study and neuropathological findings. She had complained of headaches, dizziness, nausea, vomiting as well as attention and memory loss, and anxiety, sadness and a slowing down in the performance of daily activities. The symptoms rapidly became worse and she was referred to a neurosurgery department for consultation. She was successfully neurosurgically operated on. She was examined with the use of ne uro psycho logical tests three times: the first examination was conducted before the neurosurgical operation, the second two weeks after, and the third half year after the neurosurgical operation. In the first examination by the standard Polish version of the Mindstreams™ Interactive Computer Tests disturbances for all the tested cognitive functions occurred. The greatest changes were to occur however in the areas of visual-spatial functions. attention, executive functions and memory. In the second test, a return to the norm was achieved for the disturbed cognitive and executive functions. In the third examination (half a year after the neurosurgical operation), the cognitive and executive functions were still not bad, but had slightly decreased. Similar trend was observed in HRQoL. A significant difference in the health profile between the 1 st and 2 nd as well as between 1 st and 3 rd examination was detected for the eight SF-36 domains - HRQoL was improved. While only slight but no significant changes occurred between 2 nd and 3 rd examination. HRQoL was still not bad, but had slightly decreased. The patient after the neurosurgical operation of glioblastoma multiforme (GBM) is capable of carrying out daily activities, but shows some level of reduced complains for functional capacity, pain, general health and vitality, emotional and social functioning for mental health which has led to the impaired HRQoL.

Wybrane aspekty jakości życia pacjentów hemodializowanych

89%

Piernikowska A.

Innowacje w Pielęgniarstwie i Naukach o Zdrowiu

2023

vol. 8

issue 1

59-87

Introduction. Renal replacement therapy performed as part of dialysis among patients allows replacing the work of their renal failure. However, due to the aggravating nature of this method of treatment, it significantly affects the modification of patients' quality of life. Aim. The purpose of research in this study was to verify selected aspects of the life of hemodialysis patients using a hemodialysis catheter and – venous arteriovenous fistula. Material and methods. The studies were conducted among 100 patients undergoing hemodialysis. They used the diagnostic survey method, estimation method, techniques: survey and estimation scale, and the WHOQOL - BREF questionnaire with the proprietary record. Results. Research results indicate a varied level of quality of life for hemodialysis patients in different domains of their functioning. Conclusions. Most hemodialysis patients present an average level of satisfaction with the quality of their lives. They perceive the individual, general perception of quality of life better than the individual general perception of their own health. The quality of life of patients undergoing hemodialysis does not depend significantly on their age, education and place of residence. Significantly higher assessment of the quality of life within the environmental domain was presented by persons in relationships, the lowest assessment within the social domain was made by widows / widowers. The quality of life of patients undergoing hemodialysis does not depend significantly on the cause, method and time of renal replacement therapy.

Wstęp. Terapia nerkozastępcza realizowana w ramach dializoterapii wśród pacjentów umożliwia zastąpienie pracy ich niewydolnych nerek. Jednak z uwagi na obciążający charakter tej metody leczenia wpływa ona istotnie na modyfikację jakości życia pacjentów. Cel pracy. Celem badań pracy była weryfikacja wybranych aspektów życia pacjentów hemodializowanych przy użyciu cewnika do hemodializ oraz przetoki tętniczo – żylnej. Materiał i metody. Badania przeprowadzono wśród 100 pacjentów poddawanych hemodializie. Wykorzystano w nich metodę sondażu diagnostycznego, metodę szacowania, techniki: ankietowania i skali szacunkowej oraz kwestionariusz WHOQOL - BREF z autorską metryczką. Wyniki. Wyniki badań wskazują one na zróżnicowany poziom jakości życia pacjentów hemodializowanych w różnych domenach ich funkcjonowania. Wnioski. Pacjenci hemodializowani w większości prezentują przeciętny poziom zadowolenia z jakości swojego życia. Postrzegają oni indywidualną, ogólną percepcję jakości życia lepiej, aniżeli indywidualną ogólną percepcję własnego zdrowia. Jakość życia pacjentów poddawanych hemodializie nie zależy istotnie od ich wieku, wykształcenia i miejsca zamieszkania. Istotnie wyższą ocenę jakości życia w ramach domeny środowiskowej prezentowały osoby pozostające w związkach, najniższej oceny w ramach domeny socjalnej dokonywali wdowy/wdowcy. Jakość życia pacjentów poddawanych hemodializie nie zależy istotnie od przyczyny, metody i czasu prowadzenia leczenia nerkozastępczego.

Using QALY indicator in oncology on the example of chosen countries

75%

Giermaziak W., Głowala K., Ubysz D., Królak A.

Acta Poloniae Pharmaceutica - Drug Research

2018

vol. 75

issue 3

A very important tool to evaluate value of medical procedures is measuring the quality of life. One of the quality life measurement tools is QALY, particularly important in cancerous diseases, palliative care and cases of long term after-effects of disease. All around the world, public budgets associated with medications are gradually increasing, hence the regulations that increase the supervision over these expenses. Reimbursement principles concerning medicinal technologies are regulated statutorily. Any drug medical technology reimbursed from public funds is subject to a pharmacoeconomic assessment. The most restrictive requirements of ICER (cost/QALY) rating and formal ‘rigid’ cost-effectiveness thresholds apply in Great Britain and Poland. Regardless of the universality and utility, the QALY unit has limitations that may be particularly important during economical assessment of proceedings methods in oncology. It should be also stressed out that there is currently no alternative to QALY – the only common and universal measure of therapeutic effects in different clinical situations. The purpose of the current review is presentation of using QALY in oncology in different countries. The economic aspect of QALY, problems with using it, as well as advantages and disadvantages of using it in end of life period have been considered.

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1 Acta Neuropsychologica

1 Acta Poloniae Pharmaceutica - Drug Research

1 Innowacje w Pielęgniarstwie i Naukach o Zdrowiu

1 2023

2 2018

1 Adamek D.

1 Giermaziak W.

1 Góral-Półrola J.

1 Głowala K.

1 Herman-Sucharska I.

1 Królak A.

1 Morga R.

1 Moskała M.

1 Piernikowska A.

1 Pąchalska M.

1 Ubysz D.

Search results

HEALTH-RELATED QUALITY OF LIFE OF A PATIENT FOLLOWING NEUROSURGERY ON GLIOBLASTOMA MULTIFORME (GBM)

Wybrane aspekty jakości życia pacjentów hemodializowanych

Using QALY indicator in oncology on the example of chosen countries