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The bovine kappa-casein (CASK) gene is considered a potential marker for quantitative trait loci (QTL) in dairy cattle.A large amount of research has been performed to explore the nature and variation of the CASK gene and its possible applications in cattle breeding.The purpose of this review is to sum up the knowledge of all known aspects of the CASK gene; molecular structure and function, poltmorphism and allele frequency, methods of genotyping and possibilities of the use of CASK polymorphism in dairy cattle breeding.
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