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The potential of Fluorine 19F in in Targeted Therapy

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Bartusik-Aebisher D., Aebisher D., Podgórski R., Leksa N.
Acta Poloniae Pharmaceutica - Drug Research
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2019
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vol. 76
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issue 6
939-943
EN
Fluorine-19 (19F) can provides critical information about the mobility of the drug and drug uptake in cancer tissue when used together with 19F Magnetic Resonance Imaging (19F MRI) in vitro or in vivo. This review is aimed at the current limitations of drugs such as quantitative visualization during treatments of tumor cells. The main rationale about the utility of 19F MRI is visualization of fluorinated drug and fluorine conjugates on the cellular in vitro and in vivo levels.
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