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Biotechnologia
|
1999
|
issue 4
107-116
EN
Recent development of research conducted in Japan into computer applications in bio-process engineering is summarized, specially focusing on the application of knowledge engineering approaches to bio-process control. The issues of methodological investigation, their applications in process development, and examples of industrial applications of expert systems, artificial neural networks, fuzzy theory, and genetic algorithm are thoroughly reviewed, and some representative recent works are introduced more extensively.
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