Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl
Preferences help
Polish version English version Language
enabled [disable] Abstract
Number of results

Results found: 2

Number of results on page
first rewind previous Page / 1 next fast forward last

Search results

Search:
in the keywords:  DNA SYNTHESIS
help Sort By:

help Limit search:
first rewind previous Page / 1 next fast forward last
1

The role of calcium in DNA synthesis and development of mouse preimplantation embryos in vitro

100%
Zwierzchowski L., Czlonkowska M., Sladkowska E., Guszkiewicz A.
Folia Biologica
|
1992
|
vol. 40
|
issue 3-4
103-108
EN
The effect of calcium upon embryonic growth was studied using cultured mouse preimplantation embryos. Both morphological development of the embryos and embryo DNA synthesis were shown to be dependent on the in the medium in which the embryos were grown. Reduction of the calcium concentration completely blocked cell division and blastocyst formation in the cultured embryos, but only moderately inhibited embryo DNA synthesis. Trifluoperazine, a calmodulin antagonist, strongly inhibited the calcium - dependent DNA synthesis in the embryos. On the other hand, the drug only slightly affected the morphological development of the embryos. These results demonstrate that calcium independently affects two different aspects of the embryo development, i.e. DNA synthesis and cell division. It is suggested that the former effect is calmodulin-dependent, while the latter involves the calcium-dependence of metabolite transport through the cell membranes.
2

The induction of bcl-2 gene expression in human lymphocytes in vitro

75%
Kocki J., Rozynkowa D.
Genetica Polonica
|
1994
|
vol. 35
|
issue 1-2
115-125
first rewind previous Page / 1 next fast forward last
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.