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Cytolysins and homologous proteins produced by Gram-negative bacteria. II.Hemolysins of Aeromonas sp., Morganella sp., as well as homologous proteins of Gram-negative bacteria

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Rozalski A.

Postępy Higieny i Medycyny Doświadczalnej

1996

vol. 50

issue 4

363-374

This article presents the genetic determination, synthesis and activation of hemolysins produced by mentioned above bacteria, as well as the possible role of these toxins in the pathogenicity. All these cytolysins are related to RTX proteins presented in the previous paper. The short information about cytotoxic proteins from other Gram-negative bacteria (P. aeruginosa, K. pneumoniae, Vibrionaceae, G. vaginalis) and homologous proteins from E. chrysanthemi and R. leguminosarum biovar viciae are also included.

Cytolisins and homologous proteins produced by Gram-negative bacteria. I. Hemolysis and leukotoxins of Escherichia coli, Bordatella pertusis, Pasteurella haemolytica and Actinobacillus sp.

100%

Rozalski A.

Cytolysins produced by Gram-negative bacteria belong to the pore forming bacterial proteins. A branch of these toxins represents RTX family of proteins. The RTX (repeats in toxin) family name has been proposed based on the common presence of tandem copies of a nine-amino acid repeat (L-X-G-G-X-G-(N/D)-D-X). The paper presents the genetics, synthesis, secretion and cytolytic activity of these toxins.

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2 Postępy Higieny i Medycyny Doświadczalnej

2 1996

2 Rozalski A.

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Cytolysins and homologous proteins produced by Gram-negative bacteria. II.Hemolysins of Aeromonas sp., Morganella sp., as well as homologous proteins of Gram-negative bacteria

Cytolisins and homologous proteins produced by Gram-negative bacteria. I. Hemolysis and leukotoxins of Escherichia coli, Bordatella pertusis, Pasteurella haemolytica and Actinobacillus sp.