Search results

Search:
in the keywords: CONDITIONED TASTE AVERSION

Sort By:

Limit search:

Behavioural changes after ablation of subdivisions of the rat prefrontal cortex

100%

Mogensen J., Divac I.

Acta Neurobiologiae Experimentalis

1993

vol. 53

issue 3

439-449

Sham operated controls and four groups of subjected to of various parts of their were compared in food and water intake and four behavioural tasks. The ablations were aimed at removing the ventral prefrontal cortex, the dorsal part of the medial prefrontal cortex, the total medial prefrontal cortex, and the anterior dorsolateral (non-prefrontal) cortex. Only two groups had a significantly impaired food and water intake: the ventral prefrontal and the non-prefrontal anterolateral. The Latter group was not adipsic. Two variants of spontaneous alternation were administered in a T-maze: a non-cued version in which both arms were grey and a sued version in which one arm was white and the other black. While all ablated groups behaved like the control group on the non-aued test, the number of perseverative responses of the total anteromedial group was significantly increased in the cued version of the test. Significant group differences could be seen neither in a test of conditioned taste aversion nor in extinction of operantly conditioned bar presses. Finally, in a vertical hole-board exploration test the only significant group difference was a prolongation of the mean visit duration of the ventrally lesioned animals in comparision with all other groups. The results of the present study further indicate functional differentiation within the prefrontal cortex of the rat.

Refine search results

1 Acta Neurobiologiae Experimentalis

1 1993

1 Divac I.

1 Mogensen J.

Search results

Behavioural changes after ablation of subdivisions of the rat prefrontal cortex