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1

Viral infections - prevention and therapy

100%
Figlerowicz M.
Biotechnologia
|
2002
|
issue 1
7-23
EN
Despite extensive biomedical studies conducted during over the last decades, viral infectious diseases remain one of the most serious world heath problems. At the moment, one can distinguish three major ways of their prevention or treatment: immunisation, chemotherapy and immunomodulation. This article presents a broad spectrum of both widely used and presently developed methods of fighting viral infections.
2

Immunomodulatory effects of selected chemotherapeutics

88%
Golab J., Zagozdzon R.
Biotechnologia
|
2001
|
issue 3
78-85
EN
Chemotherapeutics are still regarded as a mainstay of antitumor strategies. A number of observations indicate that these agents might be used at low doses with the same or even better efficacy than the high-dose chemotherapy. The efficacy of the low-dose chemotherapy might be at least partly explained by the regulation of the antitumor immune response. These immunomodulatory effects might be further potentiated by combinations with selected biological response modifiers, such as recombinant cytokines (IL-2, TNF, IL-12). The effectiveness of such combinations has already proved encouraging in pre-clinical models.
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