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Effects of oral L-arginine supplementation on vasodilation and O2max in male soccer players

100%
Yaman H., Tiryaki- Sönmez G., Gürel K.
Biomedical Human Kinetics
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2010
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vol. 2
25-29
EN
Study aim: To determine the effects of oral L-arginine supplementation on vasodilation, blood flow and maximum oxygen uptake (O2max) in soccer players.Material and methods: A group of 24 healthy male soccer players aged 20 - 26 years volunteered to participate in the study. The subjects were randomly assigned into 3 groups: experimental, placebo and control. Experimental group was given L-arginine (6 g orally) and the placebo group - starch (6 g orally) daily for a week; subjects from the control group remained untreated. Before the test and at the end of the week blood samples were collected, and systemic blood pressures, blood flows and maximal oxygen uptake (O2max, by Queens College step test) were recorded. Blood samples were assayed for HDL, LDL, triglyceride and urea concentrations. The study was conducted in a randomised, single-blinded, placebo-controlled fashion consisting of 7-day treatment periods.Results: Oral supplementation of L-arginine significantly (p<0.01) decreased blood pressure indices and increased O2max (p<0.01), blood flow (p<0.05), femoral artery diameter (p<0.05) and urea levels (p<0.05). There was no change in blood lipid levels (p<0.05). No significant changes were noted in the placebo and control groups.Conclusions: Oral supplementation of L-arginine may have beneficial effect on vasodilation and O2max, therefore may increase the exercise capacity of soccer players.
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The effects of vitamin E and selenium on blood flow to experimental skin burns in rats using the 133Xe clearance technique

88%
Varoglu E., Seven B., Gumustekin K., Aktas O., Sahin A., Dane S.
Open Medicine
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2010
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vol. 5
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issue 2
219-223
EN
The aim of the present experimental study was to determine and to compare the effects of vitamin E and of selenium on the blood flow to a wound region in rats, using the xenon-133 (133Xe) clearance technique. Burn wounds were made on the right thighs of rats followed by oral administration of vitamin E or selenium for a period of 10 days. The effect of vitamin E and of selenium individually on blood flow in the wound region was assessed before and after oral administration using the 133Xe clearance technique. Both vitamin E and selenium significantly increased the blood flow in the wound region (P<0.05). Our results in rats suggest that both vitamin E and selenium have beneficial effects on the skin wound healing process by increasing the skin blood flow.
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