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Synthesis and properties of new biotin compounds containing hexyltriethylene glycol chain

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Matijoška A., Charkova T., Kuodis Z., Voiciuk V., Eicher-Lorka O.
Open Chemistry
|
2012
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vol. 10
|
issue 1
113-120
EN
The synthesis of a new halogenide containing hexyltriethylene glycol chain functionalized with biotin is reported. The general possibility of this linker to use as the building block for biotinylated compounds syntheses is demonstrated. Two biotinylated esters with different properties for useful surface modification and as fluorescence probes for proteins marking were synthesized. The properties of mentioned compounds were investigated by using surface plazmon resonance ellypsometry and fluorescence spectroscopy.
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