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Biotechnologia
|
1999
|
issue 2
145-166
EN
Biosynthesis of bacteriocins by lactic acid bacteria is determined by culturing conditions, like medium composition, pH, temperature, cultivation method, metabolite concentration, cell density, phase of growth and time of fermentation. Generally, bacteriocins are produced during the logarithmic or stationary phase of growth. The culturing conditions influence both the amount of bacteriocin production as well as their antibacterial activity. In the paper numerous examples of culturing requirements for individual bacteriocins production are presented.
EN
Bacteriocins are heterogeneous group of ribosomally synthesized proteins or peptides produced by different bacteria that kill or inhibit growth of other bacteria. The interest in bacteriocins results from their potential application as biopreservatives in food to inhibit the growth of spoilage or pathogen bacteria In this paper identification of these metabolites and their physical and biochemical properties, including spectrum of activity, terms of size, amino acid sequence, modes of action and immunity mechanisms are presented.
EN
Bacteriocins are antimicrobial proteins or peptides produced by both Gram-positive and Gram-negative bacteria. Many of these metabolites are active towards closely related species, but some of them are able to inhibit bacteria not related with bacteriocin producer, including food pathogens such as Listeria monocytogenes or Clostridium botulinum. The most studied bacteriocins are those produced by lactic acid bacteria, but an increased interest in bacteriocins synthesized by propionibacteria has been observed in the last years. In this paper, the data on molecular characteristics and biochemical properties of actually known bacteriocins produced by this group of bacteria is presented.
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