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A meta-analysis of the efficacy of exercise in reducing symptom of fatigue in patients with multiple sclerosis

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Ghuntla T. P., Dholakiya J. R., Georgiew F., Jankowicz-Szymańska A.
Health Promotion & Physical Activity
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2024
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vol. 27
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issue 2
23-29
EN
Introduction: Multiple sclerosis is chronic disorders of the central nervous system. One of the most common complaints in patients with multiple sclerosis is fatigue. Exercise can improve physical performance. Studies suggests that exercise activity can be beneficial for fatigue in patients with multiple sclerosis. Objectives: To study influence of exercise activities on fatigue in patients with multiple sclerosis. Methods: Researchers used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines for reporting systematic reviews and meta-analysis. Researchers searched articles on PubMed, Google scholar and by manual search. Searched articles were screened for relevancy. By use of inclusion and exclusion criteria potential articles were selected. Results: Out of 229 articles, finally 5 studies included in current meta-analysis. Exercise activities has effect on fatigue. Modified Fatigue Impact Scale (MFIS) score: SMD = 0.47, 95% CI = 0.06–0.87. Conclusion: Exercise activities can provide beneficial effect on fatigue in patients with multiple sclerosis. This can help patients with multiple sclerosis in daily life activities There is wide scope for further studies to evaluate beneficial effects of exercise activities.
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