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Structure and biosynthesis of human salivary mucins.

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Zalewska A., Zwierz K., Żółkowski K., Gindzieński A.
Acta Biochimica Polonica
|
2000
|
vol. 47
|
issue 4
1067-1079
EN
Human salivary glands secrete two types of mucins: oligomeric mucin (MG1) with molecular mass above 1 MDa and monomeric mucin (MG2) with molecular mass of 200-250 kDa. Monomers of MG1 and MG2 contain havily O-glycosylated tandem repeats located at the central domain of the molecules. MG1 monomers are linked by disulfide bonds located at sparsely glycosylated N- and C-end. MG1 are synthesized by mucous cells and MG2 by the serous cells of human salivary glands.
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