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Background: A low prevalence of TB and MDR-TB was indicated from the retrospective study conducted at Pandit Dindayal Upadhyay Government Medical Hospital (PDUGMH) in Gujarat between 2018 and 2022. Mycobacterium tuberculosis causes tuberculosis (TB), the most lethal infectious disease in the world that affects people of all ages. Material and methods: From its TB & Chest Department, a total of 5,624 TB notification records were reviewed for the study, of which 5207 were TB positive, with 3586 (68.87%) males and 1621 (31.13%) females. Results: Amongst positive patients, 215 were diabetic, and 454 were HIV positive. Of 5207 TB-positive patients, 2982 (57.27%) had pulmonary TB. Extra Pulmonary TB showed the maximum number of patients with an infected lymph node. Age between 15 to 29 years was the leading affected age group, with a high peak in 2019. Drug resistance of Shorter Multidrug Resistance (RR-TB) was observed with a maximum of 0.8% (n = 42) patients and of Oral longer MDR/FQ with a minimum of 0.1% (n = 3) patients. Conclusions: Findings indicate that in these five years, patients treated at PDUGMH exhibited a tuberculosis prevalence of 92.59%, with a corresponding rate of multidrug-resistant TB standing at 1.48%. A comprehensive assessment is required to depict the burden and guide initiatives for eradication.
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