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Infertility and marker chromosomes: Application of molecular cytogenetic techniques in a case of inv dup(15)

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Vulcani-Freitas T. M., Gil-da-Silva-Lopes V. L., Varella-Garcia M., Maciel-Guerra A. T.
Journal of Applied Genetics
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2006
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vol. 47
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issue 1
89-91
EN
We report on a phenotypically normal man with infertility, whose 47,XY,+mar karyotype was studied by spectral karyotyping (SKY) and fluorescence in situ hybridization (FISH) using a chromosome-15-specific probe (LSI SNRPN). By these techniques, the marker chromosome was identified as a small inv dup (15). Possible causes for male infertility in this case are discussed.
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