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Phosphodiesterases of cyclic GMP

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Wroblewska H., Gorczyca G. W. A., Gorczyca W. A.
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vol. 55
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issue 5
615-627
EN
Phosphodiesterases of cyclic nucleotides (PDEs) are enzymes hydrolyzing cGMP, cAMP or both and are regulated in several different ways. In this paper we summarize current data on structure, cellular and tissue localization, regulation and function of different PDE families that hydrolyze cGMP.
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