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Radiation Stability of the BSA Modified Biocompatible Magnetic Fluid

100%
Tomašovičová N., Haysak I., Kováč J., Kubovčíková M., Závišová V., Timko M., Okunev A., Zorkovská A., Kopčanský P.
Acta Physica Polonica A
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2014
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vol. 126
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issue 1
262-263
EN
The aim of the presented work was to investigate the stability of biocompatible magnetic fluid, i.e. water-based magnetic fluid containing magnetite nanoparticles stabilized by surfactant sodium oleate and modified by bovine serum albumin (BSA) after electron irradiation. Samples with the same concentration of Fe_{3}O_{4} but different mass ratio BSA/Fe_{3}O_{4} (w/w=0.25, 1.0 and 2.5) were studied. The electron irradiation caused about 10% reduction of the saturation magnetization in the samples with w/w BSA/Fe_{3}O_{4} ratio of 0.25 and less than 5% in the samples with w/w BSA/Fe_{3}O_{4} ratio of 1 and 2.5.
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Magnetic Properties of Biocompatible Magnetic Fluid after Electron Irradiation

81%
Tomašovičová N., Haysak I., Koneracká M., Kováč J., Timko M., Závišová V., Okunev A., Parlag A., Fradkin A., Sakhno V., Kopčanský P.
Acta Physica Polonica A
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2012
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vol. 121
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issue 5-6
1302-1304
EN
The magnetic particles in the water-based magnetic fluids were sterically stabilized by natrium oleate to prevent their agglomeration and consequently the adsorption of poly-ethylene-glycol (PEG) was carried out to improve the biocompatibility of the magnetic particles. Two sets of samples were prepared. The first set of the samples was with different molar weight of PEG (Mw = 400, 1000, 10000 and 20000) at the constant weight ratio of PEG/Fe_3O_4 = 0.25 and the second one was with different weight ratio of PEG/Fe_3O_4 and constant molar weight of PEG (Mw = 1000). The samples were irradiated with 20 Gy. The same reduction of saturated magnetization (about 10%) after electron irradiation with 20 Gy was observed for all prepared samples.
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