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EN
In Africa, few studies are interested in unilateral spatial neglect (NSU) in Parkinson's disease. However, this syndrome is a deficit to detect, respond to or orientate towards meaningful stimuli (Heil- man, KM 1973), observable after an injury affecting the non-dominant hemisphere for language. The significant handicap it entails justifies the need for early diagnosis and care. The NSU study is mo- tivated by its link with neurocognitive phenomena that are important on the theoretical level (attention, visuospatial and perceptual awareness). The objective is to study USN in Parkinson's pa tients, followed and hospitalized at the Neurology Department of Hassan II University Hospital in Fez. The visual-graphic test that has been used to detect this pathology is that of Bell's test. The test focuses on the detection of targets placed among several stimuli on a sheet of A4 paper. The material included 120 people: 60 Parkinsonian patients: 34 men (56,7%), and 26 women (43,3%) and 60 control subjects: 34 men (56,7%), and 26 women (43,3%). The groups were matched by age and sex. Different aspects of neglect have been observed throughout the Bell's test. It was found that total omission of bell figures was significantly influenced by age, being less frequent in the 35-49 age group in both groups, and higher in the elderly (50-80 years), as well the level of education. It have been reduced considerably with the increase in education. The hand used and the laterality had no effect; t = 3.76 degrees of freedom (df) = 108.27 and p = 0.000. Unilateral spatial neglect has a negative effect in subjects with Parkin- son's disease. It deserves to be systematically sought for a better clinical evaluation and therapeutic management of the patients.
EN
Handwriting is a component of the complex language that came about late in the history of mankind and which develops late in human beings. Numerous works have raised changes in both the graphic and kinematic characteristics of writing. Although, age does not modify the lexical and syntactic parameters of language, it can however modify its spatial structure, especially pressure and speed. Many neurodegenerative pathologies, especially Alzheimer's disease, are characterized by a progressive disorganization of writing. Depending on the cognitive stage of the dementia, the graphic gesture deteriorates as does the spatial construction. Objective: Our study aims at assessing the characteristics of Arabic writing in a healthy Moroccan population and to compare it to people with mild to moderate Alzheimer's disease. Our objective is to help health professionals detect early cognitive deterioration in neurodegenerative diseases by analyzing the graphic gesture. Handwriting is captured on a graphic tablet (WACOM) and is analyzed "online" as a sequence of acquired signals (position, pressure, speed and pen inclination) in Moroccan patients with mild to moderate Alzheimer's disease and these were compared to those of normal volunteers. We performed a first analysis of the results from 18 Alzheimer's patients compared to 18 control subjects. The results reveal differences between the control and Alzheimer's groups. AD subjects had lower speeds and accelerations compared to the control subjects. The time spent on paper and in the air was significantly greater in the AD subjects. This preliminary analysis of the results allowed us to identify distinguishing characteristics through the analysis of different handwriting parameters in order to identify the two groups studied.
EN
Parkinson’s disease can lead to disability and reduce the quality of life of its patients. The purpose of this study is to evaluate the quality of life of a group of people with Parkinson’s disease. The clinical and progressive characteristics of the disease, its motor and neuropsychological impact were evaluated in each Parkinsonian subject included in the study. A quality of life assessment was performed and collected from 60 Parkinsonian patients followed and hospitalized at Hassan II University Hospital in Fez. Different instruments were used, the Hoenh and Yahr scale and the Parkinson’s disease questionnaire (PDQ-39) UPDRS engine, MMS, clinical fact sheet. According to our results, through the different tests and scale of evaluation, we observed an impaired quality of life in the areas of physical discomfort, cognitive disorder, activity of daily living, mobility, and emotional well-being, especially in patients with duration of evolution more than 5 years. There was no significant difference between the two sexes. In addition, the severity of the disease tended to give the impression of an impaired quality of life with respect to the dimensions of activities of daily living and cognition, which is relevant to improving the quality of life patient life and clinical interventions.
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