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ROLA WITAMINY D W CHOROBACH NOWOTWOROWYCH I NEURODEGENERACYJNYCH – PRZEGLĄD LITERATURY

100%
Waszyk-Nowaczyk M., Główka E.
Farmacja Polska
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2020
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vol. 76
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issue 3
149-155
EN
In recent years, a significant increase in the incidence of cancer and neurodegenerative diseases has been observed. This is mainly because of the higher life expectancy and thus prolonged contact with risk factors, inadequate diet and lack of physical activity. Along with aging processes, the prevalence and incidence of many diseases rise dramatically. New drugs and solutions are constantly being sought that would help in particular preventing. One way could be the use of vitamin D or its analogues, which through their proven pleiotropic action, have become the focus of the interest of many scientists in the last decade. One might think that the problem of vitamin D deficiency should affect a small part of the population, due to health campaigns carried out and the availability of many OTC preparations with vitamin D in various forms. Research, however, confirms that the need for vitamin D supplementation is overlooked by healthcare professionals, and its deficiencies are widespread worldwide and affect all ages. It is very meaningful problem. It is important to check the concentration of this vitamin in the blood, which in the case of low levels can be correlated with potential health problems. The influence of vitamin D on physiological processes, confirmed by numerous studies and scientific publications, and thus also the prevention of numerous diseases, is an important argument indicating the need for patient education on how to take it regularly. For this reason, preventive actions carried out by professional medical staff, including pharmacists in community pharmacies, regarding awareness of the important role of vitamin D and its impact on our health are important. Patient counseling may have a significant effect on improving quality of life. This article discusses some mechanisms of antiproliferative, neuroprotective and immunomodulatory activity of active vitamin D derivatives on the example of selected cancers, Alzheimer's disease, and multiple sclerosis.
PL
W ostatnich latach obserwuje się znaczny wzrost zachorowań na nowotwory i choroby neurodegeneracyjne. Wciąż poszukuje się nowych leków i rozwiązań, które pomogłyby zwłaszcza w zapobieganiu tym chorobom. Jednym ze sposobów może być stosowanie witaminy D lub jej analogów, które poprzez swoje udowodnione wielokierunkowe działanie, stały się w ostatniej dekadzie przedmiotem zainteresowania wielu naukowców. Można by pomyśleć, że problem niedoboru witaminy D powinien dotyczyć niewielkiej części populacji, ze względu na przeprowadzane kampanie zdrowotne i dostępność wielu preparatów OTC z witaminą D w różnej postaci. Badania potwierdzają jednak, że potrzeba suplementacji witaminy D jest pomijana przez pracowników służby zdrowia, a jej niedobory są powszechne na całym świecie i dotykają wszystkich grup wiekowych. Duże znaczenie ma sprawdzanie stężenia tej witaminy we krwi, co w przypadku niskiego poziomu można skorelować z potencjalnymi problemami zdrowotnymi. Potwierdzony w licznych badaniach i publikacjach naukowych wpływ witaminy D na procesy fizjologiczne, a przez to także na zapobieganie licznym chorobom, jest istotnym argumentem wskazującym na potrzebę edukacji pacjentów na temat jej regularnego przyjmowania. Z tego powodu istotne są akcje profilaktyczne prowadzone przez fachowy personel medyczny, w tym także przez farmaceutów w aptekach ogólnodostępnych, dotyczące uświadamiania pacjentom ważnej roli witamy D i jej wpływu na nasze zdrowie. W niniejszym artykule omówiono niektóre mechanizmy działania antyproliferacyjnego, neuroprotekcyjnego i immunomodulującego aktywnych pochodnych witaminy D na przykładzie wybranych chorób nowotworowych, choroby Alzheimera oraz stwardnienia rozsianego.
2
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INFLUENCE OF COMMUNITY PHARMACY SPECIALIZATION ON PROFESSIONAL PHARMACEUTICAL COUNSELLING SCHEME IN PHARMACIES IN POZNAN AND WARSAW (POLAND)-PILOT STUDY

81%
Waszyk-Nowaczyk M., Szukalska B., Guzenda W., Michalak M.
Acta Poloniae Pharmaceutica - Drug Research
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2019
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vol. 76
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issue 2
375-380
EN
Education of community pharmacy workers is a very important part of everyday practice, especially in professional counselling (PC) which brings many health benefits for the patients. The aim of the study was to investigate if the community pharmacy specialization has an influence on the scope and quality of counsels given by pharmacy workers during PC scheme implementation in community pharmacies. The research was carried out between May and November 2017. After PC scheme implementation in community pharmacies, an anonymous questionnaire was administered to 245 pharmacy workers in Poznan and Warsaw (241 women, 4 men): 146 pharmacists (143 women, 3 men) and 99 pharmacy technicians (98 women, 1 man). In the conducted study, 14.7% of pharmacists had community pharmacy specialization (according to Polish law). Pharmacists with a community pharmacy specialization referred patients more often to physicians (p<0.0001), as well as after earlier physician consultation (p<0.0001). Furthermore, they often noticed the interaction between drugs in patients’ self-treatment and in the treatment ordered by a physician (p≤0.001). The indication of medication contraindications after a physician consultation was also significantly higher within pharmacists with specialization (p<0.0001). It can be noted that pharmacists with community pharmacy specialization were asked more often for self-treatment consultation and after physician visits (p<0.0001). Development of PC in Polish community pharmacy, especially among pharmacy owners well-educated in community pharmacy specialization, may help to increase safety of pharmacotherapy.
3
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OPINIONS OF PHARMACISTS ON COMMUNITY PHARMACY-BASED HEALTH SCREENINGS FOR COMMON CHRONIC DISEASES

81%
Waszyk-Nowaczyk M., Skura O., Michalak M., Ratka A.
Acta Poloniae Pharmaceutica - Drug Research
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2018
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vol. 75
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issue 3
EN
Rising number of chronic diseases worldwide requires improvement of patients’ care system, especially in disease prevention and health promotion. Therefore it is justified to broaden the range of services in community pharmacies in Poland. The aim of this study was to evaluate pharmacists’ opinion about health screenings for chronic diseases in community pharmacies. Research was based on original, anonymous questionnaire administered between July 2016 and March 2017 to pharmacists (n=175; 77.7% women and 22.3% men) practicing in a community pharmacy in Wielkopolska (n=106; 77.4% women and 22.6% men) and Zachodniopomorskie Region (n=69; 78.3% women and 21.7% men). The effect of age and gender on pharmacists’ opinions was evaluated. Among pharmacists who responded, 93.7% agreed that patients don’t have health check-ups when they don’t experience bothersome symptoms of a disease. Almost three fourth of respondents considered implementation of health screening services in pharmacy as valuable as it can have positive influence on development of pharmaceutical care. Younger pharmacists (p=0.019) who collaborate with physicians (p=0.009) were most certain about it. 80,0% of pharmacist, in particular younger one, would offer their patients the screening services (p=0.006). 79,4% pharmacists confirmed that this new service should be reimbursed by National Health Fund. Development of new health screening services in community pharmacies may help to prevent or lower the risk of complications associated with common chronic diseases.
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