Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl

Refine search results

Journals help

  1. 1 Kosmos

Years help

  1. 1 2009

Authors help

  1. 1 Góral K.

  2. 1 Smalec E.

  3. 1 Wójcik E.

Preferences help
Polish version English version Language
enabled [disable] Abstract
Number of results

Results found: 1

Number of results on page
first rewind previous Page / 1 next fast forward last

Search results

help Sort By:

help Limit search:
first rewind previous Page / 1 next fast forward last
1
Content available remote

Łamliwe miejsca chromosomu

100%
Wójcik E., Smalec E., Góral K.
Kosmos
|
2009
|
vol. 58
|
issue 1-2
135-142
EN
Fragile sites on chromosomes are the sites which exhibit tendency towards breaks and gaps under specific conditions of in vitro cultured cells, and after induction with chemical agents. They are categorised as either rare and common. Fragile sites are evolutionary conserved. They are observed in all organisms and play a significant role as far as an occurrence of gene and chromosome disorders in animals and humans is concerned, thus constituting instable regions of the genome. The instabilities may initiate inappropriate expression of genes determining various characteristics. They may give rise to developmental disorders, high mortality at an early stage of life, poorer animal liveability and reproduction as well as tumour expansions. Fragile sites constitute a subject of cytogenetic studies in diagnosing genetic disorders. They can also serve as a selection tool in an assessment of health, and identification of individuals with genetic disorders.
first rewind previous Page / 1 next fast forward last
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.