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Wody oligotroficzne w źródłach rezerwatu Struga Dobieszkowska

100%

Mordalska A., Witczak M., Ferenc T.

Folia Medica Lodziensia

2012

vol. 39

issue 1

39-50

On the basis of the example of the nature reserve "Struga Dobieszkowska" (RSD), the occurrence of natural areas such as midforest springs and streams found in Lodz Hills Landscape Park (LHLP) are discussed. The springs in the area of LHLP create ecosystems characterized by significant phytoenosic, floral and faunal diversity. These springs have preserved the highest class of water purity (oligotrophic waters). The presence of the commonest for this class of water - saprobes e.g. the bryophytes genus Brachythecium, Gammarus pulex as well as typical groups of diatons has been observed. At present the areas adjacent to LHLP are subjected to significant anthropopressure which can result in the contamination of groundwater in this area.

Na przykładzie rezerwatu przyrody ,,Struga Dobieszkowska” (RSD) omówiono występowanie na terenie Parku Krajobrazowego Wzniesień Łódzkich (PKWŁ) naturalnych obszarów przyrody, takich jak śródleśne źródliska i strumienie. Źródliska na terenie PKWŁ tworzą środowisko (ekosystemy) charakteryzujące się znaczną różnorodnością fitocenotyczną, florystyczną i faunistyczną. Źródliska te zachowały najczystszą klasę czystości (wody oligotroficzne). Zanotowano obecność najpospolitszych dla tej klasy wód saprobów: mszaki z rodzaju Brachythecium, kiełż zdrojowy (Gammarus pulex) oraz typowe zbiorowiska okrzemek. Obecnie tereny przyległe do PKWŁ poddawane są silnej antropopresji, której skutkiem może być zanieczyszczenie wód podziemnych w tym regionie.

Genetic Variations of the CTNNA1 And The CTNNB1 Genes in Sporadic Colorectal Cancer in Polish Population

76%

Sygut A., Przybyłowska K., Ferenc T., Dziki Ł., Spychalski M., Mik M., Dziki A.

Polish Journal of Surgery

2012

vol. 84

issue 11

560-564

Experimental as well as clinical observations have demonstrated that the E-cadherin/catenin complex is a powerful inhibitor of invasion. Abrogation of this pathway is implicated in the carcinogenesis of several malignancies, especially colorectal cancer. The aim of the study was to determine the CTNNA1 and the CTNNB1 mutations and its relationship to clinical and pathological features of sporadic colorectal cancer (CRC) in Polish patients. Material and methods. Paired tumor and normal tissue samples from 110 sporadic CRC patients undergoing resective surgery were prospectively studied for the alpha catenin (CTNNA1) gene and beta catenin (CTNNB1)gene mutations by PCR/single strand conformation polymorphism (SSCP). Results. The CTNNA1 gene alteration in exon 7 were detected in 4 samples and in exon 3 of CTNNB1 gene were found in 3 samples. There was a trend at the limit of statistical significance associating younger age at diagnosis (<50) with CTNNA1 and the CTNNB1 mutations. The mutation of CTNNB1 seemed to occur more frequently in the proximal colon than distal. The CRC patients with CTNNA1 mutation had a significantly increased lymph node metastasis. On the other hand, there was no correlation between mutations and the other clinical variables (e.g. sex, grade and depth of invasion). Conclusion. Although we found a low frequency of mutations in the CTNNA1 and the CTNNB1 genes, but the analysis the relationship with clinical and pathological features of CRC patients may indicated an association of these mutations with the risk and progression of CRC.

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1 Folia Medica Lodziensia

1 Polish Journal of Surgery

2 2012

2 Ferenc T.

1 Dziki A.

1 Dziki Ł.

1 Mik M.

1 Mordalska A.

1 Przybyłowska K.

1 Spychalski M.

1 Sygut A.

1 Witczak M.

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Wody oligotroficzne w źródłach rezerwatu Struga Dobieszkowska

Genetic Variations of the CTNNA1 And The CTNNB1 Genes in Sporadic Colorectal Cancer in Polish Population