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A rare case of isolated melanoma of the sphenoid sinus

100%

Ścierski P., Koniewska A., Misiołek M., Ścierski W., Lisowska G.

Polski Przegląd Otorynolaryngologiczny

2024

vol. 13

issue 3

22-25

Introduction: Sphenoid sinus melanoma is extremely rare – only 7 cases have been described in the available literature. Aim: We present the next case of a 77-year-old female with melanoma of the left sphenoid sinus treated in our ENT Department. Case study: A 77-year-old female was admitted to our department due to the histologically confirmed left sphenoid sinus malignant melanoma. During admission, the patient was treated with Pembrolizumab at the Oncology Center in Gliwice. In our department, she underwent endoscopic surgery of the left sphenoid sinus and nasopharynx six times. The patient’s last admission on 04/2023 was caused by the heavy epistaxis from the left nasal cavity. She died less than a year after the last surgical intervention (04/2023) due to the generalization of the neoplastic disease. Conclusions: Malignant melanoma of the sphenoid sinus is an extremely rare neoplasm. The endoscopic resection of the tumor remains the treatment of choice. However, newer modalities like biologic and immunomodulatory treatments are being studied. The 5-year survival rates in these cases are only 10–15%.

The use of pulse transit time in diagnostics of sleep-disordered breathing in children

73%

Kawalski M., Ścierski P., Marków M., Tażbirek M., Morawiec B., Kawalski H., Namysłowski G., Misiołek M., Ścierski W.

Polish Journal of Otolaryngology

2024

vol. 78

issue 3

6-16

Introduction: Sleep is the physiological state of the body where proper morphology and duration are indispensable for human functions throughout both, physical and mental spheres. Disordered breathing during sleep impairs its morphology and results in major disorders in any age group. Adverse effects of Obstructive Sleep Apnea Syndrome in children and poor availability of centers offering children’s polysomnography call for a reliable and easily accessible screening method. Aim: The aim of the study were to evaluate the usefulness of pulse transit time in the diagnostics of disordered sleep breathing in children and to attempt to employ the parameter in screening tests. Pulse transit time is a physiological parameter determining the time needed for the pulse wave to travel between two measurement points. Material and methods: Enrolled in the retrospective study were 153 patients (100 boys and 53 girls) suspected of obstructive sleep apnea syndrome who underwent polysomnography at I. Mościcki ENT Hospital in Chorzów. Results: Statistically significant relations between apnea/hypopnea index and pulse transit time were observed in both, individual age groups and all of the patients. Pulse transit time results proved a negative correlation with apnea/hypopnea index values commonly accepted as a parameter concluding the polysomnography procedures. Conclusions: The results of the study indicate that pulse transit time measurements may find application in screening tests of sleep-disordered breathing in children.

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1 Polish Journal of Otolaryngology

1 Polski Przegląd Otorynolaryngologiczny

2 2024

2 Misiołek M.

2 Ścierski P.

2 Ścierski W.

1 Kawalski H.

1 Kawalski M.

1 Koniewska A.

1 Lisowska G.

1 Marków M.

1 Morawiec B.

1 Namysłowski G.

1 Tażbirek M.

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A rare case of isolated melanoma of the sphenoid sinus

The use of pulse transit time in diagnostics of sleep-disordered breathing in children