Search results

Sort By:

Limit search:

An introduction to DNA chips: principles, technology, applications and analysis.

100%

Gabig M., Węgrzyn G.

Acta Biochimica Polonica

2001

vol. 48

issue 3

615-622

This review describes the recently developed GeneChip technology that provides efficient access to genetic information using miniaturised, high-density arrays of DNA or oligonucleotide probes. Such microarrays are powerful tools to study the molecular basis of interactions on a scale that would be impossible using conventional analysis. The recent development of the microarray technology has greatly accelerated the investigation of gene regulation. Arrays are mostly used to identify which genes are turned on or off in a cell or tissue, and also to evaluate the extent of a gene's expression under various conditions. Indeed, this technology has been successfully applied to investigate simultaneous expression of many thousands of genes and to the detection of mutations or polymorphisms, as well as for their mapping and sequencing.

The Escherichia coli RNA polymerase α subunit and transcriptional activation by bacteriophage λ CII protein

61%

Gabig M., Obuchowski M., Ciesielska A., Latała B., Węgrzyn2 A., Thomas M. S., Węgrzyn G.

Acta Biochimica Polonica

1998

vol. 45

issue 1

271-280

Refine search results

2 Acta Biochimica Polonica

1 2001

1 1998

2 Gabig M.

2 Węgrzyn G.

1 Ciesielska A.

1 Latała B.

1 Obuchowski M.

1 Thomas M. S.

1 Węgrzyn2 A.

Search results

An introduction to DNA chips: principles, technology, applications and analysis.

The Escherichia coli RNA polymerase α subunit and transcriptional activation by bacteriophage λ CII protein