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Wysiłek fizyczny – lek bez recepty: znaczenie kinezyterapii w profilaktyce i leczeniu wysiłkowego nietrzymania moczu u kobiet (w aneksie zestaw proponowanych ćwiczeń)

100%

Dalewska M., Kasicka-Jonderko A., Jonderko K., Augustyniak H.

Annales Academiae Medicae Silesiensis

2013

vol. 67

issue 6

384-392

Stress urinary incontinence in women is a serious social problem and because of its prevalence should be considered a civilization disease. The article discusses the causes of disorders of pelvic statics leading to stress incontinence. The principles of prevention of this disease are presented, and in an illustrated appendix, a set of exercises useful in the prevention and kinesitherapy of stress urinary incontinence is proposed.

Wysiłkowe nietrzymanie moczu u kobiet stanowi poważny problem społeczny i ze względu na częstość występowania ma charakter choroby cywilizacyjnej. W artykule omówiono przyczyny zaburzeń statyki narządu rodnego, powodujące wysiłkowe nietrzymanie moczu. Przedstawiono zasady profilaktyki tego schorzenia, a w ilustrowanym aneksie zaproponowano zestaw ćwiczeń przydatnych w profilaktyce i kinezyterapii wysiłkowego nietrzymania moczu.

PTEN – clinical significance in colorectal cancer

76%

Copija A., Waniczek D., Walkiewicz K., Głogowski Ł., Augustyniak H., Nowakowska-Zajdel E.

OncoReview

2016

vol. 6

issue 2

A86-90

Phosphatase and tensin homolog deleted on chromosome ten (PTEN) is a human suppressor gene. Its protein product is a bispecific phosphatase playing the complex role in the cell cycle regulating processes and apoptosis by the mechanism of signal transduction into the cell via tyrosine kinase B signaling pathway (PI3K/Akt/mTOR). Reduction or loss of PTEN function is implicated in the pathogenesis of many malignancies, including colorectal cancer. A gradual decrease in the function of PTEN in the sequence of transformations: normal tissue–polyp–adenocarcinoma – disseminated cancer was indicated. The relation between the PTEN loss and the higher clinical severity of colorectal cancer was observed, i.a. higher TNM status and higher tendency to form metastases, leading in some of the studies to shortened patients survival during the observation period. The potential predictive value of the PTEN function loss for the EGFR-targeted therapy in patients with advanced colorectal cancer is the subject of controversy. The potential application of PTEN assessment in clinical practice as a prognostic and/or predictive factor requires further well-designed prospective studies on larger patient population, using the unified methodology. The aim of the study is to summarize the current knowledge on the role of PTEN gene and PTEN protein in the pathogenesis of colorectal cancer and the role of PTEN in clinical practice.

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1 Annales Academiae Medicae Silesiensis

1 OncoReview

1 2016

1 2013

2 Augustyniak H.

1 Copija A.

1 Dalewska M.

1 Głogowski Ł.

1 Jonderko K.

1 Kasicka-Jonderko A.

1 Nowakowska-Zajdel E.

1 Walkiewicz K.

1 Waniczek D.

Search results

Wysiłek fizyczny – lek bez recepty: znaczenie kinezyterapii w profilaktyce i leczeniu wysiłkowego nietrzymania moczu u kobiet (w aneksie zestaw proponowanych ćwiczeń)

PTEN – clinical significance in colorectal cancer