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1

POTENTIAL USE OF CHITOSAN – BASED MATERIALE IN MEDICINE

100%

Kucharska M., Ciechańska D., Niekraszewicz A., Wiśniewska-Wrona M., Kardas I.

Progress on Chemistry and Application of Chitin and its Derivatives

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2010

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vol. 15

169 - 176

EN

Polysaccharides are macromolecular polymers that manifest ability toward the forming of fibres, film and coatings. Some of their specific properties like biodegradability and biocompatibility make them suitable for medical application. Chitin, chitosan and alginates are basic polymers mostly used in the preparation of medical biomaterials. In the Institute of Biopolymers and Chemical Fibres (IBWCh) multidirectional investigations are in full swing concerned with the use medical of polysaccharides and their various useful forms. The research includes amongst: multifunctional dressing materials, implants and other polysaccharide biomaterials.

2

POLYMER BIOCOMPOSITES USED IN BEDSORES TREATMENT

100%

Wiśniewska-Wrona M., Kucharska M., Kardas I., Bodek A., Bodek H.

Progress on Chemistry and Application of Chitin and its Derivatives

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2011

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vol. 16

111 - 120

EN

Investigations are presented in the preparation of composite dressing material based on two biopolymers -chitosan and sodium alginate with the addition of sulfanilamide as medication designed for the healing of bedsores. The dressing was prepared in the form of film. The biopolymers used in the construction of the film make the dressing biodegradable and resorbable in the wound’s environment. Mechanical properties of the film were tested: thickness, extension strength, tenacity and elongation at maximum stress The ability of the material to match the wound was examined, too, as well as the transmission of water vapor. Sulfanilamide as bacteriostatic agent was added to the prepared composites. Mechanical and sorption properties of the composite dressings with addition of the active substance depend largely on their composition. The sorption properties were tested before and after addition of the medication .The release of the medication is intricate and proceeds according to kinetics of first order. Susceptibility of the composite materials to hydrolytic and enzymatic degradation was assessed.

3

UTILIZATION OF BIODEGRADABLE POLYMERS FOR PERIPHERAL NERVE RECONSTRUCTION

73%

Kardas I., Marcol W., Niekraszewicz A., Kucharska M., Ciechańska D., Wawro D., Lewin-Kowalik J., Właszczuk A.

Progress on Chemistry and Application of Chitin and its Derivatives

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2010

|

vol. 15

159 - 168

EN

Peripheral nerve injuries are one of frequent cause of disability. Results of surgical procedures are not still completely satisfactory, though fast development of microsurgical technician improve their efficiency. One of the major problems in surgical treatment of the peripheral nerve injuries is ends coaptation in the case of large loss of nerve tissue. And so finding substitute implants not rejected by the organism for the recipient and providing with the success is necessary of regeneration. Recently, several synthetic nerve guide implants have been introduced and approved for clinical use to replace autologous transplants. This alternative therapy is based on pioneering studies with experimental nerve guides. This paper present a review of published studies involving biodegradable nerve guides.

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3 Progress on Chemistry and Application of Chitin and its Derivatives

1 2011

2 2010

3 Kardas I.

3 Kucharska M.

2 Ciechańska D.

2 Niekraszewicz A.

2 Wiśniewska-Wrona M.

1 Bodek A.

1 Bodek H.

1 Lewin-Kowalik J.

1 Marcol W.

1 Wawro D.

1 Właszczuk A.

POTENTIAL USE OF CHITOSAN – BASED MATERIALE IN MEDICINE

POLYMER BIOCOMPOSITES USED IN BEDSORES TREATMENT

UTILIZATION OF BIODEGRADABLE POLYMERS FOR PERIPHERAL NERVE RECONSTRUCTION