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A Review on the Role of Selected Functional Foods in Obesity Management

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Evbuomwan S. A., Omotosho O. E.
World News of Natural Sciences
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2022
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vol. 40
1-12
EN
Obesity is a foremost but preventable cause of deaths globally. It is a significant risk factor for the development of cardiovascular diseases, particularly heart failure, and diabetes. Natural products such as some foods, fruits, medicinal plants have been known to be functional in the management of Obesity. This article is aimed at reviewing the weight loss and anti-obesity potentials of Ginger (Zingiber officinale), Avocado (Persea americana) and Green Tea (Epigallocatechin gallate, EGCG). Google Scholar, PubMed, NCBI and Elsevier databases were searched from 2004 to 2020 using specific keywords. Searching was restricted to English language. Seventeen articles (Eleven human studies and six animal studies) were included in this review. Majority of the research papers that were considered in this review supported the weight loss and anti-obesity potentials of these natural products in obese human and animal subjects by lowering most of the clinical markers of obesity. Some of the anti-obesity mechanisms proposed by the authors include suppression of lipogenesis, inhibition of ghrelin secretion, e.t.c. This article also established the need for future trials.
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Roles and Mechanisms of Docosahexaenoic Acid (DHA) in Neurodevelopment, Neuronal Functions, Learning and Memory

81%
Evbuomwan S. A., Omotosho O. E., Mgbojikwe I.
World News of Natural Sciences
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2022
|
vol. 40
104-119
EN
Docosahexaenoic acid (DHA) is an omega-3 fatty acid which is a major constituent of the brain, retina and skin in terms of structure. DHA can be produced from the metabolic synthesis of alpha linolenic acid (ALA) or gotten from breast milk, fatty fishes, or oil from algae. Studies have shown that DHA is an essential nutrient for normal functioning of the brain. It is the major omega-3 fatty acid present in brain tissues and is known to have effects on neurotransmitters, synaptic transmission, and signal transduction. Also, certain DHA metabolites are biologically active molecules that protect the tissues from oxidative injury and stress. DHA is also known to carry out important membrane neuronal functions such as Phospholipid synthesis, membrane fluidity, neuronal survival, regulation of gene expression and modulation of enzyme activity in the brain. Therefore, DHA needs to be taken at developmental stages of human life such as period of pregnancy, lactation and even childhood for proper development and functioning of the brain.
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