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Superficial mycoses in the Nis region, Southeast-Serbia

100%
Otasevic S., Đorđević J., Ranđelović G., Ignjatović A., Stojanović P., Zdravković D., Marković R.
Open Medicine
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2011
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vol. 6
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issue 5
665-671
EN
The aim of the study is to investigate the most frequent cause of superficial mycoses in patients from the territory of city Niš Southeast Serbia in the period from 1998 to 2010. A total of 3223 samples from 2887 patients with suspected dermatomycoses were examined. Superficial mycoses were diagnosed using standard microbiology techniques (conventional microscopy and cultivation). Dermatophytes were determined on the basis of their macroscopic and microscopic morphological and morphometric characteristics. Morphometric characteristics were obtained by Laboratory Universal Computer Image Analysis system (Lucia M, 1996). Species of genus Candida were identified using the test of production of germ tube in sera, by growth on comertial chromatogen medium (Chromotogenic Candida, Liofichem/Bacteriology products, Italy) and by using Auxacolor TMBioRad, France. The results were elaborated with the statistical method of descriptive and quantitative analysis (SPSS 14.0 for Windows 2003). The prevalence of superficial mycoses was 25,1%. Dermatophytes were identified in 67.6% of all positive cultures. Microsporum canis was the most prevalent (50.3%) dermatophyte isolated, followed by Trichophyton metagrophytes var. mentagrophytes (35.4%). Yeast genus Candida has become a more frequent cause of superficial fungal infection since 2001. and C. albicans was the dominant yeast (61.1%).
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Asymptomatic carriers of clostridium difficile in serbian population

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Stojanović P., Stojanović N., Kocic B., Stanković-Đorđević D., Babić T., Stojanović K.
Open Medicine
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2012
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vol. 7
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issue 6
769-774
EN
The aim of the research was to determine the intestinal carriers of C. difficile in different human population groups in Serbia. The research enrolled 877 persons with formed stools: (newborn children in maternity hospitals for up to two weeks old) (23), group A; children aged from two weeks to two years (121), group B; children aged two to 10 years (54), group C, healthy individuals aged 10 and over (516), group D; patients hospitalized for at least 48 hours (100), group E; staff of the Clinical Center in Nis, Serbia, (63), group F. The toxins A and B of C. difficile were detected by ELISA-ridascreen Clostridium difficile Toxin A/B (R - Biopharm AG, Darmstadt, Germany). The toxin A of C. difficile was detected using ColorPAC Toxin A test (BectonDickinson, New Jersey, USA). Out of the total number of persons (877), the carriers of certain types of toxin-producing strains of C. difficile were distributed as: 6.04% (A−/B−), 1.83% (A+/B+) and 0.11% (A−/B+). In most groups (5/6), the dominance of non-toxigenic (A−/B−) isolates was established, with the rate of carriers 1.75 – 30.43% depending on the group. Toxigenic isolates were prevalent only in the group F in relation to non - toxigenic (7.94% versus 4.76% of persons). In other groups, the carriers of toxigenic strains ranged from 0.00 – 17.45%. The presence of asymptomatic intestinal carriers of C. difficile in the human population, indicate the possible reservoirs and sources of infection.
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Erratum to: Superficial mycoses in the Nis region, Southeast-Serbia

84%
Otasevic S., Miladinovic-Tasic N., Đorđević J., Ranđelović G., Ignjatović A., Stojanović P., Zdravković D., Marković R.
Open Medicine
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2011
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vol. 6
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issue 6
830-830
EN
The original version of the article was published in Central European Journal of Medicine Volume 6, Number 5, 665–671, DOI: 10.2478/s11536-011-0052-y. Unfortunately, the original version of this article contains mistakes in the Authors names section. There should be: Suzana Otasevic1, Natasa Miladinovic-Tasic1, Jovana Đorđević1, Gordana Ranđelović1, Aleksandra Ignjatović1, Predrag Stojanović1, Dragan Zdravković2, Roberta Marković2
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