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An unusual presentation of corneal intraepithelial neoplasia

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Marticorena-Álvarez P., Garrido Ceca G., Celdrán Vivancos D. A.
OphthaTherapy
|
2020
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vol. 7
|
issue 4
302-304
EN
Introduction: Conjunctival/corneal intraepithelial neoplasms are premalignant lesions usually showing conjunctival or limbal involvement. We report the rare case of an isolated corneal intraepithelial lesion. Clinical case: An 80-year-old woman with an elevated, avascular, well-demarcated grey corneal plaque. After epitheliectomy and alcohol, the excised lesion was identified as a high-grade epithelial neoplasia. Treatment was topical interferon α-2b for 1 month without recurrences. Conclusions: A well-defined greyish corneal opacity should always raise suspicion of an intraepithelial neoplasia. In the present case, epitheliectomy and topical recombinant interferon proved successful.
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