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The impact of inflammatory flares in dry eye disease

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Izdebska J., Samelska K.
OphthaTherapy
|
2023
|
vol. 10
|
issue 3
179-182
PL
Dry eye disease is a condition treated commonly by most of the ophthalmologists. The current understanding of the disease puts impact on its newly discovered components – ‘flares’. Flares are defined as exacerbations of dry eye disease. They take place in response to the triggers, which may be environmental or internal factors. During the ‘flare’ the immunological response is being activated and the patients experience the worsening of the symptoms. The introduction of the anti-inflammatory treatment (e.g. topical hydrocortisone solution) is the effective treatment in the cases of inflammatory state exacerbations.
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Rational therapy of ocular surface bacterial infections with fluoroquinolones

100%
Trojacka E., Izdebska J.
OphthaTherapy
|
2022
|
vol. 9
|
issue 2
119-123
PL
Prawidłowa powierzchnia oka ma szereg mechanizmów chroniących ją przed inwazją bakterii chorobotwórczych. W przypadku przełamania fizjologicznej bariery dochodzi do rozwoju zakażenia i stanu zapalnego. Jednymi z częstszych chorób zakaźnych powierzchni oka są bakteryjne zapalenia spojówek i rogówki. Terapia tych schorzeń powinna bazować na racjonalnym stosowaniu antybiotyków o szerokim spektrum działania przeciwbakteryjnego, wysoce skutecznych i bezpiecznych. Wszystkie powyższe cechy maja fluorochinolony: ofloksacyna, lewofloksacyna i moksyfloksacyna.
EN
There are many mechanisms, that protect healthy ocular surface from invasion of pathogenic bacteria. Infection and inflammation develop on the ocular surface in case of damaging natural defensive barrier. One of the most common ocular surface infections are bacterial conjunctivitis and keratitis. Rational therapy of these diseases should be based on antibiotics that have broad antimicrobial spectrum, good efficacy and safety. All these qualities have fluoroquinolones: ofloxacin, levofloxacin and moxifloxacin.
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