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1

Continuous sterilization of medium for bacitracin biosynthesis

100%
Cywinska U., Iciek J., Chmiel A., Stolarek P.
Biotechnologia
|
1993
|
issue 2
76-82
EN
The aim of the paper was to estimate the applicability of continuous sterilizationto the improvement of bacitracin production technology. Preliminary investigations were carried out and the effects of application of thermal continuous sterilization of substrates were estimated. The quality of sterilized substrates was assessed in fermentation tests. Bacitracin biosynthesis was carried out on a substrate sterilized by both batch and continuous method. In laboratory investigations a substrate sterilized by the continuous method enabled to increase antibiotic production by 30% on the average as compared to the yield obtained using a batch sterilized substrate. On an industrial scale, for the same inoculation material the production was even higher by 80%.
2

Bacteriae sporogenesis in the aspect of biotechnological processes

100%
Libudzisz Z., Stobinska H., Oltuszak E., Iciek J.
Biotechnologia
|
1993
|
issue 2
83-96
EN
The process thermal sterilization is very important for both: food processing technology and for many biotechnological processes. It should be carried out in such a way as to efficiently destroy microorganisms and to restrict the decrease of nutritive value of the sterilized media. The paper presents physiological and biochemical conditions of thermal resistance of spores. Special attention has been paid to environmental factors which either protect or enhance the thermal destruction of spores.
3

Advantages of the application of continuous media sterilization in gibberellic acid production

100%
Iciek J., Cywinska U., Stolarek P.
Biotechnologia
|
1993
|
issue 3
89-98
EN
The paper presents advantages of the application of continuous of media for production. It is estimated that the profit resulting from the application of continuous thermal sterilization of this medium in the Pharmaceutical Plant "Polfa" at Kutno will exceed I billion zlotys a year.
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