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Biogenic Magnetite Nanoparticle Ensemble Use in MRI Diagnostics

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Strbak O., Krafcik A., Teplan M., Gogola D., Kopcansky P., Frollo I.

Acta Physica Polonica A

2014

vol. 126

issue 1

388-389

We present a simple analytical tool, which allows the calculation of the MRI diagnostics feasibility of the biogenic magnetite nanoparticles. Elevated levels of these particles are usually linked to the pathological processes, especially to neurodegenerative disorders. We showed theoretically that the biogenic magnetite itself is not sufficient for the non-invasive diagnostics and must be extended with the total iron incorporated in other biological structures.

Comparison of Iron Oxide-Related MRI Artifacts in Healthy and Neuropathological Human Brain Tissue

84%

Masarova M., Krafcik A., Teplan M., Strbak O., Gogola D., Boruta P., Dobrota D., Frollo I.

Acta Physica Polonica A

2017

vol. 131

issue 4

1108-1110

The aim of this study is to clarify whether clinical magnetic resonance imaging data can be utilised to evaluate the pathological processes associated with disrupted iron homeostasis, such as neurodegenerative processes or cirrhosis. Although MRI has the potential to become a non-invasive biomarker of such pathology, new quantification methods must be introduced. Our findings confirmed that it is possible to detect significant difference between healthy and pathological tissue from standard T2 weighted MRI protocols.

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2 Acta Physica Polonica A

1 2017

1 2014

2 Frollo I.

2 Gogola D.

2 Krafcik A.

2 Strbak O.

2 Teplan M.

1 Boruta P.

1 Dobrota D.

1 Kopcansky P.

1 Masarova M.

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Biogenic Magnetite Nanoparticle Ensemble Use in MRI Diagnostics

Comparison of Iron Oxide-Related MRI Artifacts in Healthy and Neuropathological Human Brain Tissue