Objective: Sphenopalatine ganglion block remains a noninvasive therapeutic option to treat diverse facial pain syndromes. The aim of this case report was to verify the effectiveness and safety of three-dimensional (3D) injection guide for sphenopalatine ganglion block in a tongue cancer patient. Case report: A 53-year-old man presented with a large squamous cell carcinoma of the right base of the tongue, classified cT4N2M0 and exhibiting excruciatin facial pain. A botulinum toxin injection was performed following Dr. Yoshida’s method, using a 3D injection guide. Conclusions: Sphenopalatine ganglion block with 3D injection guide can be an effective treatment against cancer pain. In this case report a complete withdrawal of painkillers was obtained less than 24 hours after botulinum toxin injection.
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