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2017
|
vol. 131
|
issue 5
1199-1203
EN
Soft magnetic composites are used in a wide range of applications working in different environmental conditions, between others, in different temperatures. Nowadays, devices often work in cryogenic temperatures. The paper shows influence of liquid nitrogen temperature on mechanical properties of soft magnetic composites prepared from ABC100.30 powder bonded by epoxy resin. Mechanical properties of samples were measured in room and liquid nitrogen temperatures. Compressive strength and transverse rapture strength increase with decreasing temperature. This type of soft magnetic composite can be applied in magnetic circuits of devices working in cryogenic temperatures. The results of measurement show that new devices, especially electric machines, working in these temperatures can be designed with higher mechanical loadings than devices working at room temperature.
EN
Introduction: Detection of human cytomegalovirus (CMV, HHV-5) DNA in clinical specimens is considered a cornerstone in the diagnosis of HHV-5 disease. The present study compared two quantitative methods used for diagnosing cytomegalovirus infection in a 21-year-old woman with chronic myeloid leukemia after an unrelated umbilical cord blood transplantation. Materials and Methods: Blood samples were tested for the presence of HHV-5 DNA using the LightCycler PCR, the quantitative Eclipse? CMV DNA Detection Kit, and a qualitative in-house PCR assay using primers that amplify part of the HHV-5 MIE gene. Results: Results from samples containing a low cytomegalovirus load were more accurate with the LightCycler test than those obtained with the Eclipse? test, which underestimated the viral load of samples containing low DNA copy numbers. Conclusions: These findings underline the value of novel PCR methods used in current therapeutic procedures and in monitoring antiviral therapy with nucleoside analogs. The high level of sensitivity, specificity, accuracy, and rapidity provided by the LightCycler instrument are favorable for the use of this system in the detection of HHV-5 DNA in clinical specimens.
EN
Human herpesvirus 6 (HHV-6) has been recognized as a potentially significant pathogen in hemopoietic stem cell transplant (HSCT) recipients. Different clinical manifestations have been described, including fever, skin rash, bone marrow suppression, and encephalitis. Materials and Methods: A retrospective review of a group of 26 adult recipients of allogeneic HSCTs was conducted. Serum samples taken before transplant were examined for the presence of specific anti-HHV-6 IgM and IgG antibodies. After transplantation, quantitative real-time PCR was used to determine viral load in plasma samples from days 0?180 post-transplant. Results: HHV-6 DNA was detected in plasma samples in 8 (30%) of the 26 recipients between days 18 and 40 after transplantation. All of them developed fever of unknown origin and over 50% had graft-versus-host disease features. Three individuals from this group died during detectable HHV-6 viremia. Another two recipients showed a single positive PCR result at a later time. Infection with HHV-6 was thus confirmed in 10 (38.5%) of the 26 graft recipients. Conclusions: There is a high frequency of detectable HHV-6 viral load in stem cell transplant recipients in Poland. Further investigation to monitor HHV-6 reactivation in graft recipients will be important to improve outcome for these patients.
5
76%
EN
A multiferroic tunnel junction (MFTJ) is a promising device for future memory systems with discrete and different logic states which are controlled by a combination of electric and magnetic fields. The goal of ongoing research is to present ferroelectric and ferromagnetic properties, especially at room temperature (RT), represented as high values of tunnel electroresistance (TER) and tunnel magnetoresistance (TMR). A key aspect is the appropriate preparation of a sample allowing epitaxial growth. The thin layers were prepared by pulsed laser deposition on atomically smooth monocrystalline SrTiO₃ (STO) substrates. The ferromagnetic metal layers La_{0.67}Sr_{0.33}MnO₃ (LSMO) are separated by a layer of a ferroelectric insulator - BaTiO₃ (BTO). The same structure of LSMO, BTO and STO (perovskite) and a similar lattice constant make it possible to obtain high-quality heterostructures. Magnetic measurements confirm differences in the magnetic coercivity of the top and bottom LSMO layer, which allows to obtain their parallel and antiparallel magnetization orientation. A modification of the interfaces of BTO by thin MgO layer enables an increase in the value of the TER effect.
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