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Mosquito larvicidal and ovicidal properties of Pelargonium graveolens L. Herit. (Family: Geraniaceae) essential oil against three mosquito species

100%
Dhanasekaran S., Prabhahar C., Baranitharan M., Shanmugavel G.
World News of Natural Sciences
|
2022
|
vol. 43
1-10
EN
The use of botanicals as an alternative to the chemical compounds is gaining tremendous momentum because of its multifarious advantages. In view of its increasing interest, an attempt was made in the present study to assess the larvicidal and ovicidal potential of important plant like P. graveolens against three mosquito species. The third instar larvae were exposed to different concentrations (i.e. 10, 20, 30, 40, 50 ppm) of methanol, diethyl ether, chloroform and ethyl acetate oil extracts of seed of P. graveolens plant. The mortality was recorded after 24 hrs exposure and LC50 and LC90 were determined. The ovicidal activity was determined against three mosquito species to different concentrations ranging from 70–350 ppm lower than the laboratory conditions. The present investigation revealed that the LC50 values methanol, diethyl ether, chloroform and ethyl acetate extracts of P. graveolens against An. stephensi larvae were 21.54, 24.21, 26.34 and 22.83 mg/L respectively. Ovicidal activity of methanol extract was assessed by assessing the egg hatchability. Highest concentrations 210, 280 and 350 ppm of extract exhibited 100% ovicidal activity. The results clearly show that larvicidal and ovicidal activity was dose reliant. The highest larvicidal and ovicidal activity against An. stephensi was obtained with methanol extract of P. graveolens.
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Nephroprotective role of Potentilla reptans L. aqueous extract on paracetamol - induced kidney nephrotoxicity in male mice

76%
Muthulingam M., Prabhahar C., Senthilmurugan S., Pugazhendy K., Vijayan P., Baranitharan M.
World News of Natural Sciences
|
2021
|
vol. 39
76-85
EN
Nephroprotective effects (NPE) of simple Potentilla reptans - aqueous leaf extract (Pr-ALE) leaves on Paracetamol induced kidney poisonousness in wistar rats. Adult male wistar rats (weight range (WR): 200-220g) were divided into 6 groups (n=6). Paracetamol (PA) and Silymarin (SY) stayed managed intraperitoneally arranged the 5th day to rats in all groups but the normal control. Furthermore, a significant nephroprotective (NP) of the aqueous leaf extract (ALE) and oral dose of PA and SY. Pr-ALE did not mortality or significant changes in the body weight. Progression of nephrotoxicity (NT) induced by PA in rats was interfered by Pr-ALE managed, and these effects were correspond to those managed with SY. This is the first record on NPE of Pr against PA-induced NT.
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