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Antisense oligonucleotides: from the bench to the patients

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Skorski T., Nieborowska-Skorska M., Szczylik C., Calabretta B.
Biotechnologia
|
1996
|
issue 4
108-115
EN
We describe here tha current state of progress toward gene-directed antisense-based cancer therapy targeting BCR/ABL, oncogene, primarily from the viewpoint of initial proof-of-concepts studies in animal models of human leukemias and phase I clinical investigations.
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