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Potential role of bioactive compounds in the prevention of coronavirus: an overview

100%
Senthilkumar V., Ilavenil K. K.
World News of Natural Sciences
|
2023
|
vol. 50
42-51
EN
This study highlights the importance of natural products in drug development, particularly Indian medicinal herbs with high biological potential. Major immunity-developing plant species were collected from the literature. These substances must be synthesized in the lab to enhance the human immune system to fight new viruses like novel corona to promote sustainable processes with little damage. Nature has bestowed numerous plant species with bioactive chemicals that can be utilized safely and effectively to treat various ailments in all living organisms. India, due to its diverse climate, is home to many plant species that possess medicinal properties. Some of the bioactive compounds found in Indian traditional medicine include tannins, phenols, terpenoids, flavonoids, esters, and other small chemicals. These compounds are known to exhibit biological activity and have been utilized in traditional medicinal practices in India.
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Investigating the antibacterial and antifungal properties of few organic moieties: a comprehensive analysis

81%
Nisha S., Saravanan M., Ilavenil K. K.
World News of Natural Sciences
|
2023
|
vol. 50
33-41
EN
The existing work reveals the novel character of organic compounds like 4-Methoxyphenoxyacetic acid and p-dihydroxybenzene. The compounds were investigated for their antibacterial and antifungal prospective against gram-positive bacteria. At increasing doses of 2-Methoxyphenoxyacetic acid, the zone of inhibition for Salmonella paratyphi was (30 mm/ml) at 100 µl and p-dihydroxybenzene is more resistant to bacterial such as Bacillus subtilis (38 mm/ml), Enterococcus faecalis (40 mm/ml), Mucor (42 mm/ml), Aspergillus niger (40 mm/ml). The docking investigation was carried out using Auto Dock 4.2.6; interactions between hydrogen atoms and the smallest ligands with macromolecules had the lowest binding energies.
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