Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl

Refine search results

Journals help

  1. 667 Acta Neurobiologiae Experimentalis

  2. 413 Folia Biologica

  3. 412 Postępy Higieny i Medycyny Doświadczalnej

  4. 7 Archivum Immunologiae et Therapiae Experimentalis

  5. 4 Progress on Chemistry and Application of Chitin and its Derivatives

More...
Years help

  1. 4 2023

  2. 3 2015

  3. 21 2010

  4. 36 2009

  5. 92 2008

More...
Authors help

  1. 51 Przybos E.

  2. 28 Warchalowska-Sliwa E.

  3. 25 Komala Z.

  4. 25 Maryanska-Nadachowska A.

  5. 18 Lachowska D.

More...
Preferences help
Polish version English version Language
enabled [disable] Abstract
Number of results

Results found: 1506

Number of results on page
first rewind previous Page / 76 next fast forward last

Search results

help Sort By:

help Limit search:
first rewind previous Page / 76 next fast forward last
1
Content available remote

Visual and auditory attentional capture are both sluggish in children with developmental dyslexia

100%
Facoetti A., Lorusso M. L., Cattaneo C., Galli R., Molteni M.
Acta Neurobiologiae Experimentalis
|
2005
|
vol. 65
|
issue 1
61-72
EN
Automatic multimodal spatial attention was studied in 12 dyslexic children (SRD), 18 chronological age matched (CA) and 9 reading level matched (RL) normally reading children by measuring reaction times (RTs) to lateralized visual and auditory stimuli in cued detection tasks. The results show a slower time course of focused multimodal attention (FMA) in SRD children than in both CA and RL controls. Specifically, no cueing effect (i.e., RTs difference between cued?uncued) was found in SRD children at 100 ms cue-target delay, while it was present at 250 ms cue-target delay. In contrast, in both CA and RL controls, a cueing effect was found at the shorter cue-target delay but it disappeared at the longer cue-target delay, as predicted by theories of automatic capture of attention. Our results suggest that FMA may be crucial for learning to read, and we propose a possible causal explanation of how a FMA deficit leads to specific reading disability, suggesting that sluggish FMA in dyslexic children could be caused by a specific parietal dysfunction.
2
Content available remote

Sources and mechanisms of cytoplasmic oxidative damage in Alzheimer's disease

100%
Marlatt M., Lee H., Perry G., Smith M. A., Zhu X.
Acta Neurobiologiae Experimentalis
|
2004
|
vol. 64
|
issue 1
81-87
EN
While evidence supports a pathogenic and proximal role for oxidative stress in Alzheimer's disease, the causes and consequences of reactive oxygen species that promote oxidative damage have not been directly demonstrated. Co-incident with the reduced energy metabolism during the development of the disease, some of the key mitochondrial enzymes have shown deficient activity in AD neurons, which may lead to increased ROS production. However, we found that oxidative damage occurs primarily within the cytoplasm rather than in mitochondria. Given that SOD activity is increased in AD mitochondria and that metal ions such as iron and copper are enriched in susceptible neurons, we hypothesize that mitochondria, as a source, provide hydrogen peroxide, which, as an intermediate, once in the cytoplasm, will be converted into highly reactive hydroxyl radicals through Fenton reaction in the presence of metal ion and cause damage in cytoplasm.
3
Content available remote

St John's wort (Hypericum perforatum) counteracts deleterious effects of the chronic restraint stress on recall in rats

100%
Trofimiuk E., Walesiuk A., Braszko J. J.
Acta Neurobiologiae Experimentalis
|
2006
|
vol. 66
|
issue 2
129-138
EN
This study aimed at verifying a hypothesis that St. John's wort (Hypericum perforatum) alleviates stress-induced memory impairments. Administration of Hypericum perforatum (350 mg kg-1 daily for 21 days) significantly enhanced recall of passive avoidance behavior (PAB), but had no effect on the acquisition of conditioned avoidance responses (CARs). Rats stressed chronically (2 h daily for 21 days) displayed diminished recall of the PAB and this effect was abolished by St John's wort. Chronic administration of the ?equivalent' to the stress dose of exogenous corticosterone (5 mg kg-1 daily for 21 days) also impaired recall of PAB, and this effect was also reversed by Hypericum perforatum. None of our treatments produced significant motor coordination impairments as tested in a ?chimney' test. It appears that H. perforatum prevents stress-induced deterioration of memory in rats.
4

Pregnancy, microchimerism, and autoimmune disease

100%
Nowakowska B.
Postępy Higieny i Medycyny Doświadczalnej
|
2002
|
vol. 56
|
issue 2
123-126
EN
Microchimerism is defined by the presence within an individual of a low level of cells derived from a different individual. The main, natural source of microchimerism is pregnancy. The migration of fetal cells into maternal blood during pregnancy has become an accepted fact. The maternal cells can also be found in the fetal circulation. Recent studies indicate that cells can persist in the maternal circulation for years after pregnancy. Maternal cells can also persist in het progeny. The autoimmune diseases are a diverse group of disorders. Many of them are of unknown etiology. Women are disproportionately affected by autoimmune disease and the incidence of some autoimmune disease in women peak following childbearing years. The integration of observation from differing fields of medicine has led to the consideration that microchimerism may be involved in the pathogenesis of some autoimmune diseases. Early results offer support for a potential role of microchimerism in SSc. The aim of this paper is to present current knowledge about this problem.
5
Content available remote

The presence of coherence in sympathetic and phenic activities in a developing mammal

100%
Gootman P. M., Hundley B. W., Sica A. L.
Acta Neurobiologiae Experimentalis
|
1996
|
vol. 56
|
issue 1
137-145
EN
To determine whether are devalopment changes in the baroreceptor and central respiratory modulation of sympathetic activity, we used ordinary and partial cohernce spectral analyses on cervical and splanchnic sympathetic activity in swine 1-36 days old. Removal of barareceptor influences from cervical sympathetic and splanchnic spectra using partialization shows that 3-6 Hz peaks are due to baroreceptors since coherence decreased in more then 19 days old while remaining unchanged in less then 2 weeks old piglets. The 8-12 Hz band (present in normal coherence after 21 days) was revealed in piglets less then 14 days old after removal of respiratory modulation by partialization; similarly increrased coherence was also observed in the 16-18 Hz band through 3 weeks. Thus, use of partial power and coherency is useful tool for unmasking the complex relationships found in developing SYMP outflows. These results suggest that there is a period of reorganization within the SYMP rhythm generating circuits, which may be essential for normal development.
6
Content available remote

Single-fibre electromyography SFEMG at different firing rates in myasthenia with and without thymoma

100%
Emeryk-Szajewska B., Rowinska K., Michalska T., Strugalska H.
Acta Neurobiologiae Experimentalis
|
1993
|
vol. 53
|
issue 1
305-311
EN
The single fibre EMG differences during motor axonal stimulation at different firing rates were studied in myasthenic patients:15 with, and 15 without thymoma. 10 healthy volunteers were also examined. Conventional repetitive stimulation EMG as well as SFEMG during weak voluntary contraction and on 10 and 20Hz stimulation was performed in every patient. The mean jitter in the control group was 30 ?s on voluntary contraction and about 22 ?s at 10 as well as at 20 Hz stimulation. In both groups of myasthenic patients under consideration SFEMG on voluntary contraction detected neuromuscular transmission disturbances of various degree. The results obtained at motor axonal stimulation (10 and 20 Hz) were unhomogeneous. In both groups jitter seemed to be slightly shorter at higher (20 HZ) frequency stimulation, probably due to facilitation but differences were significant.
7

Comparative cytogenetic study of Poecilimon brunneri Frivaldsky and P. zwicki Ramme (Phaneropteridae: Orthoptera)

100%
Warchalowska-Sliwa E., Michailova P., Peshev G.
Folia Biologica
|
1992
|
vol. 40
|
issue 1-2
33-39
EN
The karyotype of Poecilimon brunneri and P.zwicki is described. In both species it possesses the primitive character. The relative length of chromosome in P. brunneri and P. zwicki are compared. Both species have an unstable B chromosome and aberrations in autosomes. In P. zwicki the X chromosome shows euchromatic segments of different size and place.
8

Electrophysiological studies on adaptive changes of serotonin receptors using spontaneous epileptiform activity in neuronal network

100%
Bobula B., Zahorodna A., Tokarski K., Hess G.
Postępy Higieny i Medycyny Doświadczalnej
|
2002
|
vol. 56
|
issue 3
377-383
EN
Certain antidepressant medications exert effects on the serotonergic (5-HT) syste but their machanisms are still not well understood. Using extracellular ex vivo recording of spontaneous, epileptiform activity of neurons we determined changes in the reactivity of cortical and hippocampal slices to agonists of main subtypes 5-HT receptors, induced by repeated administration of the antidepressants . Repeated treatment with antidepressants enhances the 5-HT-mediated inhibition in both frontal cortex and hippocampal regions. Drugs administration induce opposite adaptive changes within 5-HT2 and 5-HT1A receptors in frontal cortex as well as in 5-HT1A and 5-HT4 receptors in the hippocampus. These effects may contribute to therapeutic effects of antidepressants administration.
9

Tumour markers in the diagnosis and monitoring of lung cancer

100%
Lawicki S., Mroczko B., Szmitkowski M.
Postępy Higieny i Medycyny Doświadczalnej
|
2002
|
vol. 56
|
issue 1
93-118
EN
Serum tumour markers may be helpful in early diagnosis of lung cancer, in the initial assesment of the extent of the disease, and in monitoring of the tumour growth or tumour volume reduction, once cancer has been diagnosed and treatment started. Recent studies have focused especially ? cytokines as a new group of tumour markers.
10
Content available remote

Various strategies of forelimb movement during contact placing reactions elicited by tactile stimulation of the different aspects of a cat's paw

100%
Czarkowska-Bauch J.
Acta Neurobiologiae Experimentalis
|
1996
|
vol. 56
|
issue 4
907-918
EN
Forelimb trajectory and the activity of eight muscles operating at the elbow, wrist and digit joints were analyzed during contact placing (CP) reactions elicited by tactile stimuli applied to the lateral (L) or medial (M) side of the cat's forepaw to verify whether a common movement strategy was used in these reactions. A tactile stimulus applied to the lateral side of the paw led, most frequently, to a short-latency activation of the elbow flexor muscles and flexor carpi radialis. Stimulation of the medial side of the paw produced either a short-latency activation of the elbow flexors or both the elbow flexor and extensor muscles. At the distal joints it most frequently activated extensor carpi ulnaris and flexor carpi radialis muscles. Different patterns of activation of the muscles during LCP and MCP reactions led to a diverse involvement of elbow flexion and extension movements at the beginning of the reactions. LCP was usually initiated by the elbow flexion movement whereas during MCP reactions the elbow flexion often appeared with a delay due to a brief co-contraction of the elbow flexor and extensor muscles which temporarily locked the elbow joint. The latter reaction was initiated by a backward/upward movement at the proximal joints accompanied by an ulnar deviation and a palmar flexion of the paw. The medio-lateral components of the movement were also clearly different in LCP and MCP reactions, both at the proximal and distal joints. The results indicate that various strategies of movement are used in CP reactions depending on the site of tactile stimulation.
11
Content available remote

Sympathetic skin response in obstructive sleep apnea syndrome

100%
Zakrzewska-Pniewska B., Przybylowski T., Byskiniewicz K., Kostera-Pruszczyk A., Droszcz W., Emeryk-Szajewska B.
Acta Neurobiologiae Experimentalis
|
1998
|
vol. 58
|
issue 2
113-121
EN
Examination of the sympathetic skin response (SSR), a non-invasive method of studying conduction in the sympathetic nervous system was performed in 15 male patients with obstructive sleep apnea syndrome (OSAS) evaluated by polysomnography who were compared with 7 non-apneic snorers and 26 controls. The aim of the study was to assess sympathetic nervous system function in OSAS, to compare the results with those found in non-apneic heavy snorers, to define the pattern of abnormalities and to study the correlations between SSR results and polysomnographic parameters. In the OSAS group the mean hand latency was significantly longer than in non-apneic snorers and healthy subjects. The most characteristic pattern of abnormalities was an absence of a foot response found in 12 of 15 OSAS patients. There were no correlations between SSR abnormalities and polysomnographic parameters. The SSR method seems to be useful in assessment of the sympathetic nervous system, especially of those parts related to sudomotor function, in OSAS.
12

Lysozyme-like activity in eggs and in some tissues of land snails Helix aspersa maxima and Achatina achatina

100%
Fiolka M. J., Witkowski A.
Folia Biologica
|
2004
|
vol. 52
|
issue 3-4
233-237
EN
Antibacterial lysozyme-like activity against Micrococcus luteus in eggs and some tissues of snails Helix aspers maxima and Achatina achatina was detected in a turbidimetric standard assay. The bacteriolytic activity in Helix aspersa maxima was higher than in Achatina achatina. After the application of the bioautography technique, several lytic zones of Micrococcus luteus were observed in both studied species. Electrophoresis in denaturing conditions followed by immunodetection of lysozyme using EWL antibodies indicated the presence of several lysozyme forms in the tested snails.
13

Changes in selected blood metabolites associated with melatonin administration in dairy goats

100%
Darul K., Kruczynska H.
Folia Biologica
|
2004
|
vol. 52
|
issue 3-4
239-241
EN
In order to examine the effect of exogenous melatonin on selected blood indices, dairy goats were given pineal gland hormone at a dose of 0.1 mg/kg body weight. Next, one and four hours after the melatonin had been administered, blood samples were collected from the goats in the control and treated groups in order to determine the levels of glucose, total cholesterol, triacyloglycerides, free fatty acids, as well as alanine and aspartate aminotransferase. The pineal gland hormone caused a significant increase in the levels of glucose, total cholesterol, triacyloglycerides and the activity of alanine aminotransferase. After melatonin administration a significant decrease in the FFA:TAG and FFA:Cholesterol blood ratios was observed. Moreover, no changes in the free fatty acid concentrations and the activity of aspartate aminotransferase were observed.
14
Content available remote

Neuropathology of variant Creutzfeldt-Jakob disease

100%
Ironside J. W., Head M. W., McCardle L., Knight R.
Acta Neurobiologiae Experimentalis
|
2002
|
vol. 62
|
issue 3
175-182
EN
The clinical, neuropathological genetic and biochemical features of variant Creutzfeldt-Jakob disease (vCJD) are compared to the 926 other cases of suspected CJD referred to the National CJD Surveillance Unit laboratory from 1990-2001. Histological studies of the central nervous system, lymphoid tissues and other organs were accompanied by immunocytochemistry for prion protein (PrP); Western blot analysis of PrPRES was performed on frozen brain tissue. The pathology of vCJD showed relatively uniform morphological and immunocytochemical characteristics, with PrP accumulation in lymphoid tissues, but not in other non-neural tissues. PrPRES accumulation in vCJD showed a uniform glycotype pattern distinct from sporadic CJD. All cases of vCJD were methionine homozygotes at codon 129 of the PrP gene. In view of the spread of bovine spongiform encephalopathy in Europe and Japan, continuing surveillance is required for all forms of CJD, with histological and biochemical analysis of suspected cases to allow an accurate laboratory diagnosis.
15
Content available remote

Spermine protects in vivo the antioxidant enzymes in transiently hypoperfused rat brain

100%
Farbiszewski R., Bielawski K., Bielawska A., Sobaniec W.
Acta Neurobiologiae Experimentalis
|
1995
|
vol. 55
|
issue 4
253-258
16

Mechanisms of fatty acid uptake by tissues

100%
Synak M., Budohoski L.
Postępy Higieny i Medycyny Doświadczalnej
|
2000
|
vol. 54
|
issue 6
797-818
EN
Fatty acids (FA) play an important role in energy metabolism. They are not only used as substrates for energy production but are also involved in many other metabolic pathways. However, the exact mechanisms by which FA are taken up by the cells are not yet fully understood. Fatty acids circulating in blood cross the cell membranes partly via a mechanism facilitated by plasma membrane proteins and partly via a passive diffusion mechanism, the former mechanism being of major importance.
17

The role of mono-amine oxidase isozymes on reserpineinduced adrenal hormone release in the pigeon (Columba livia)

100%
Chakrabarti E., Sengupta S., Dasadhikari S., Ghosh A.
Folia Biologica
|
1997
|
vol. 45
113-116
EN
The present investigation was performed to study the participation of the specific isozyme of mono-amineoxidase (MAO) during reserpine-modulated release of medullary catecholamines (CAM). This was carried out by pretreatments of pargyline and clorgyline followed by reserpine administration. The findings revealed that the pigeon adrenal contained predominantly MAO-A. Blockade of type B activity by pargyline caused a significant rise in adrenomedullary CAM content in reserpinized pigeons. However, clorgyline (an MAO-A inhibitor) administration followed by reserpine treatment showed no appreciable change in the medullary CAM level, suggesting that type B activity is mainly responsible for reserpine action on the adrenal medulla in the pigeon. In addition, reserpine was also able to decrease the glandular corticosterone content, while pargyline and clorgyline failed to alter this trend in reserpinized pigeons.
18

A comparison of nucleic acid content in Balantidium coli, trophozoites from different isolates

100%
Skotarczak B., Zielinski R.
Folia Biologica
|
1997
|
vol. 45
121-124
EN
Cytophotometric assays were performed on Balantidium coli trophozoites isolated from 30 pigs affected by acute balantidiasis (Group I) and from 30 pigs with symptom-free balantidiasis (Group II). Trophozoites from cultures obtained from Group I and II pig isolates were assayed for comparison. Comparative cytophotometric studies on nucleic acids of B.coli trophozoites isolated from acute and symptomless balantidiasis-affected pigs as well as from in vitro cultured trophozoites showed differences which could have resulted from diferences between populations in the trophozoans under investigation.
19
Content available remote

The tubulovesicular structures - the ultrastructural hallmark for all prion diseases

100%
Liberski P. P.
Acta Neurobiologiae Experimentalis
|
2008
|
vol. 68
|
issue 1
113-121
EN
Tubulovesicular structures (particles ? TVS) are the only ultrastructural marker for all prion diseases as seen by thin-section electron microscopy as opposed to ?negative-staining' techniques. TVS are spheres or short rods of approximately 27 nm in diameter. That size of TVS is also the size of filter cut-off of infectivity as judged from the ultrafiltration studies and the size of the smallest infectious unit as recently estimated. TVS have been found in all naturally occurring and experimentally induced prion diseases, including variant Creutzfeldt-Jakob disease and human familial TSEs ? fatal familial insomnia and Gerstmann-Str?ussler-Scheinker disease. In longitudinal studies, the number of neuronal processes containing TVS correlates roughly with the incubation period and with infectivity. Hence, they are readily found in hamsters infected with the 263K strain of scrapie but it is very difficult to find them in human TSEs where titer is lower. The composition of TVS is unknown but they are not composed of PrP. Their consistent presence in all TSEs suggests the unexplained role at least of TSE pathogenesis.
20

Microsporidia infect the Liophloeus lentus (Insecta, Coleoptera) ovarioles, developing oocytes and eggs.

100%
Swiatek P., Gorkiewicz T.
Folia Biologica
|
2006
|
vol. 54
|
issue 1-2
61-67
EN
In the ovarioles of Liophloeus lentus (Insecta, Coleoptera, Curculionidae) two types of bacteria and parasitic microorganisms belonging to Microsporidia have been found. This study shows that the different microsporidian life stages (meronts, sporonts, sporoblasts and spores) infect the outer ovariole sheath, trophic chambers, follicular cells, late previtellogenic and vitellogenic oocytes and eggs. In trophic chambers the parasites are very abundant and are distributed unevenly, i.e. their large mass occupies the syncytial cytoplasm between the nurse cell nuclei, whereas the neck region of the trophic chamber (which houses young oocytes, prefollicular cells and trophic cords) is almost free of parasites. The developing oocytes and eggs contain a lower number of parasites which are usually distributed in the cortical ooplasm. The gross morphology of the ovaries is similar in infected and non-infected specimens. Similarly, the presence of a parasite seems to not disturb the course of oogensis. The only difference was found in the ultrastructure of mitochondria in young previtellogenic oocytes. In the infected females they are unusual i.e. bigger and spherical with tubullar cristae, whereas in the non-infected insects they are elongated and have lamellar cristae. As oogenesis progresses the unusual mitochondria rapidly change their morphology and become similar to the mitochondria in non-infected females. Taking into account the distribution of parasites within the ovarioles, it is suggested that they infect growing oocytes via outer ovariole sheath and follicular epithelium rather than via trophic cords.
first rewind previous Page / 76 next fast forward last
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.