Search results

1

Therapeutic strategies for Alzheimer's disease based on new molecular mechanisms

100%

Religa D., Winblad B.

Acta Neurobiologiae Experimentalis

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2003

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vol. 63

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issue 4

393-396

EN

Background and objective: Alzheimer's disease (AD) ? the main cause of dementia ? is characterized by the presence of neuritic plaques containing the amyloid-beta peptide (A beta) and an intraneuronal accumulation of tubule-associated protein called tau. The current and future therapeutic strategies for AD will be discussed. Currently available treatment used in AD is based on acetylcholinesterase inhibitors, since in the course of AD there is a substantial loss in cholinergic neurons. Another registered drug used in more severe AD is NMDA antagonist ? memantine. Available strategies for AD include vitamin supplementation for reducing homocysteine levels, statins and non-steroidal anti-inflammatory drugs. The big hope of the last few years ? vitamin E and estrogen supplementation have not been proved efficient, but more studies are needed. There are several strategies aimed at acting directly on A beta or amyloid precursor protein (APP) processing: vaccination with A beta peptide, A beta passive immunization, beta and gamma secretases inhibitors. Nerve growth factors and neurotrophines could also be targeted by new therapies. Conclusions: a better understanding of the role of APP processing and folate and homocysteine in neuronal homeostasis throughout life consist revealing novel and relatively inexpensive approaches for preventing and treating AD.

2

ACCUMULATION OF P-COUMARIC ACID AND OTHER BIOACTIVE PHENOLIC ACIDS IN IN VITRO CULTURE OF RUTA GRAVEOLENS SSP. DIVARICATA (TENORE) GAMS.

100%

EKIERT H., PIEKOSZEWSKA A., MUSZYŃSKA B., BACZYŃSKA S.

Medicina Internacia Revuo

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2014

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vol. 26

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issue 102

24-31

EN

Shoot-differentiating callus culture of Ruta graveolens ssp. divaricata (Tenore) Gams was maintained on four variants of Linsmaier-Skoog (L-S) medium containing different concentrations of plant growth regulators, 1-naphthaleneacetic acid and 6-benzylaminopurine, ranging from 0.1 do 3.0 mg/l. Methanolic extracts of biomass cultured in vitro were used to determine the contents of free phenolic acids with an HPLC method. Out of eight compounds under analysis, six were shown to be present in the samples: caffeic acid, chlorogenic acid, p-coumaric acid, p-hydroxybenzoic acid, protocatechuic acid and syringic acid. Total contents of the compounds under study ranged from 124.9 to 138.7 mg/100g d.w., depending on the L-S medium variant. p-Coumaric acid was the main compound in the extracts from biomass cultured on all tested medium variants and its amounts were interesting from practical perspective (97.3-112.9 mg/100g d.w.). This compound was isolated, purified and its identity was confirmed by spectral methods. The contents of other compounds did not exceed 11.1 mg/100g d.w. Extracts of the above-ground parts of plants growing in vivo (stems, leaves, herb), analyzed for comparison, contained three phenolic acids: protocatechuic acid (52.0-88.2 mg/100g d.w.), vanillic acid (2.6 – 17.8 mg/100g d.w.) and trace amounts of syringic acid. This is the first report on the effect of growth regulators on the accumulation of free phenolic acids in biomass of R.graveolens cultured in vitro. This is also the first report documenting the isolation of p-coumaric acid from biomass of this subspecies cultured in vitro and also from any plant in vitro culture. In addition, for the first time in the above-ground parts of the plants growing in vivo phenolic acids were analyzed.

3

Analysis of the content of phenolic compounds in in vitro culture of some edible mushrooms (Basidiomycota)

100%

Muszyńska B., Kała K., Sułkowska-Ziaja K., Szewczyk A., Łojewski M., Rojowski J.

Medicina Internacia Revuo

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2015

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vol. 26

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issue 104

146-152

EN

Phenolic compounds, both derivatives of benzoic and cinnammic acid, possess biologically valuable properties: anti-inflammatory, antioxidant, anticarcinogenic and others. Studies of the accumulation of these compounds focused mostly on plant material. Rich sources of these compounds are representatives of Basidiomycota taxon. The aim of the study was qualitative and quantitative HPLC analysis of phenolic acids in biomass from in vitro culture of selected edible mushroom species belonging to the phylum Basidiomycota: Agaricus bisporus, Boletus badius, Cantharellus cibarius. The investigations revealed the presence of the following acids: p-hydroxybenzoic, syringic and galic acid. Both the composition and the amount of phenolic acids in biomass of A. bisporus and Boletus badius were diverse. The total amount ranged from 6.07 mg·100 g−1 DW in A. bisporus to 14.78 mg·100 g−1 DW in Boletus badius. Syryngic acid amounts fluctuated in the range of 1.75–9.66 mg·100 g−1 DW, with its maximum in Boletus badius. Gallic acid dominated in the biomass of the same species (5.12 mg·100 g−1 DW). p-Hydroxybenzoic acid was found in biomass from in vitro culture of A. bisporus at levels 0.70 mg/100 g DW. In biomass of in vitro culture of Cantharellus cibarius no phenolic compounds were found before and after hydrolysis. The results of HPLC analyses show that in vitro culture of B. badius and A. bisporus are a good dietary source of phenolic compounds with antioxidant activity.

4

Thyroid function in patients with Alzheimer's disease treated with cholinesterase inhibitors

100%

Kapaki E., Ilias I., Paraskevas G. P., Theotoka I., Christakopoulou I.

Acta Neurobiologiae Experimentalis

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2003

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vol. 63

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issue 4

389-392

EN

The aim of the present study was to explore a possible interplay between cholinesterase inhibitors (ChEIs) and thyroid function tests (TFTs) in patients with Alzheimer's disease (AD). We reviewed thyroid function tests in 19 patients with AD before and after treatment (Rx) with ChEIs. Immunoradiometric assays were used for measuring serum thyrotropin, free thyroxin (FT4) and free triiodothyronine (FT3). Significant differences were observed among FT3 levels according to the duration of therapy. Subtle variations in thyroid function tests - before and after therapy - could be possibly related to ChEIs-induced altered thyroid function.

5

List of ornamental and useful plants cultivated on Huahine Island, French Polynesia. Part 1

100%

Borowski J., Salachna P., Zawadzińska A.

World News of Natural Sciences

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2019

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vol. 26

36-51

EN

The article presents a list of ornamental and useful plants cultivated on Huahine Island in French Polynesia. These are flowering plants with unique visual and fragrance features, such as: Frangipani Tree, Tiare Tahiti, Gardienia, Bougainvillea, Hibiscus Tree, Blue Water Lily, Ti Plant, Ylang Ylang, Madagascar Rosy Periwinkle, Orchid. These plants belong to the traditional and cultural characteristics of Huahine Island, as in the entire French Polynesia.

6

Review on pharmacological and biological properties of Acalypha fruticosa Forssk

100%

Roja k., Ezung B., Agastian P.

World News of Natural Sciences

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2022

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vol. 42

85-93

EN

In recent times the years of conventional medicine as an alternate source for the ailment of human health and improvement of microbial resistance to the available antibiotics have recently reaffirmed the need for medicinal plants to test the antimicrobial activity. Acalypha fruticosa is one such plant that is widely known as “Chinnichedi” and shrub belonging to the Euphorbiaceae family is “Birch leaved Acalypha. The leaves and roots are used for treat skin diseases, wounds, stomach problems and poisonous bites. In view of this the present study was investigated to review the Phytochemistry, Pharmacological activity, medicinal properties and biological properties of Acalypha fruticosa.

7

Survey of benefits and constraints of urban trees in Kaduna Metropolis

100%

Ogunkalu O. A., Sodimu A. I., Sulaiman R. A., Adedire O. O.

World News of Natural Sciences

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2017

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vol. 11

19-27

EN

This study was used to assess public opinion of the economic and ecological importance of various tree species in Kaduna Metropolis, Kaduna state. A total of one hundred (100) questionnaires were randomly administered among four purposively selected towns (Angwa-Rimi and Kawo new extension in Kaduna North and Bar’nawa and Sabo in Kaduna South) within the two major local governments in the study area. Twenty-five (25) questionnaires were randomly distributed across age and sex in each of the four (4) selected towns. Of these, ninety were retrieved for analysis. Data analysis was achieved through descriptive analysis. This included frequency distribution tables, percentages and charts. The results show that the majority of the respondents were aged between (21-30) and (31-40) years, these figures representing (44.4%) and (30.0%), respectively, of the entire study population. In addition, most had secondary education (53.3%). In the stated opinions, Meliaceae occur most often. Other trees species identified in the study area include Eucalyptus spp, Azadiracta indica, Psidium guajava, Terminalia catapa, Mangifera indica, Anacardium occidentalis, Khaya senegalensis, Gmelina arboria, pinus spp, Carica papaya, Moringa olifera, Gliricidia sepium, Ficus spp, Afzelia spp, Balanite eagyptiaca, Borassus aethiopum, Persae americana, Polyantha longifolia etc. The following characteristics mark these tree species out as being economically and ecologically important: fast growth, deep rooting pattern, coppicing ability, ability to produce large crown size, tolerance to adverse weather condition, ability of trees to produce broad leaves for shade production, erosion protection, ability to provide fruits, aesthetics and beautification values. In conclusion, urban tree planting is a potential strategy to ameliorate ecological and economic concerns; thus, there is need for the dwellers in the study area to intensify efforts towards planting trees around their houses. Without this, the influx of people, urbanization and industrialization will create deleterious environmental conditions in the study area. It is recommended that efforts to make the populace aware of the economic and ecological significance of urban trees be intensified.

8

Natural products in dentistry

100%

Pytko-Polonczyk J., Muszyńska B.

Medicina Internacia Revuo

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2016

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vol. 27

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issue 107

68-75

EN

Modern medicine used many methods of treatment; one of them is phytotherapy. It is documented that plants can not only prevent many diseases, but also cure diseases. Main activities of plant materials used in dentistry are anti-inflammatory, antibacterial, antiviral, decongestant, adtringent, anti-bleeding and regenerating. The natural materials used in dentistry are mainly in the form of lotions, tinctures, infusions, toothpaste, drops and gels. The most important group of active compounds in dental formulations of natural origin include essential oils, monoterpenoides, phenolic compounds, gums, resins, tannins, flavonoids, anthocyanins, carotenoids, chlorophyll, vitamins, elements such as especially zinc and minerals such as AlK(SO4)2. It occurs naturally and is used for control of bleeding, and as an antiseptic. The ideal antimicrobial agent should be effective in removing bacteria responsible for the periodontal disease process; to have the widest possible range of action, does not cause side effects and have a prolonged activity in the oral cavity. Accordingly natural products particularly as essential oils and phenol compounds can, fulfill these tasks.

9

Zinc determination in extracts from bacopa monnieri shoot cultures into simulated gastric fluids.

100%

MUSZYŃSKA B., ROJOWSKI J., ŁOJEWSKI M., DZIWULSKA K., OPOKA W.

Medicina Internacia Revuo

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2015

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vol. 26

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issue 105

175-179

EN

Bacopa monnieri (Water hyssop) is a hydrophyte occurring in Asia and the southern US states. This plant is known in India as Brahmi and has been used in Ayurvedic medicine for 5,000 years as sedative, supporting the treatment of insomnia and improving cerebral circulation. For the biological effect in this species are responsible triterpenoids saponins – bacosides. The aim of the study was to obtain the biomass of B. monnieri shoot in vitro cultures, and then evaluating the biomass growth and content of zinc. B. monnieri derived from in vitro culture on Murashige-Skoog medium (MS) and on the same medium, but enriched in organic additives and elements may be a good source of Zinc for the human body. The experiment was also conducted on the commercial formulations containing B. monnieri. For the determination of zinc ions DP ASV method was used. It was found that the use of highly mineralized water (mineral water “Stefan” – Spa Szczawnica) for extraction of B. monnieri biomass from in vitro culture provided the highest concentration of zinc in the material and for the biomass from MS medium with the addition of As (163.52, and 167.23 mg/mL, respectively). The lowest content was found in B. monnieri biomass from MS medium supplemented with serine, and the capsules product (13.54 and 14.57 mg/mL). For extracts of B. monnieri biomass from MS medium enriched with Zn salts into digestive juices the highest concentration of zinc was determined in gastric juice (6.88 mg/mL).

10

In Vitro Micropropagation of Vernonia cinerea (L.) Less. - An important medicinal herb

100%

Ayyadurai V., Ramar K.

World News of Natural Sciences

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2019

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vol. 27

141-152

EN

In vitro micropropagation was achieved from Nodal and leaf explants of Vernonia cinerea L. on MS medium supplemented with different concentrations of BAP (1.0 to 3.0 mg/l), GA3 (1.0 to 5.0 mg/l) and KN (0.5 mg/l) for direct shoot induction. Maximum numbers of shoots were obtained from nodal and leaf explants at BAP (2.5 mg/l) GA3 (2.0 mg/l) and KN (0.5 mg/l) respectively. The multiple shoots elongation and their development were better on MS medium supplemented with 1.5 mg/l BAP and 3.0 mg/l GA3 for both the explants. The regenerated shoots were successfully rooted on MS medium supplemented with IBA 2.0 mg/1, after sequential hardening, survival rate was 91%. The in vitro raised plantlets were acclimatized and established successfully in the field.

11

Algae preparations as a source of beneficial healthy substances

100%

Jękot B., RZEWIŃSKA A., HAŁASZUK P., ROJOWSKI J., MUSZYŃSKA B.

Medicina Internacia Revuo

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2016

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vol. 27

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issue 106

4-10

EN

Algae used in OTC preparations and as functional food are available in the form of finished formulations: powders – lyophilisates, tablets, pills, capsules, and are widely used in cosmetics. In these formulations most commonly used species of algae is cyanobacteria: Arthrospira platensis (Spirulina platensis) and Arthrospira maxima (Spirulina maxima), species of red algae – red algae of the genus Porphyra: Porphyra yezoensis and Porphyra tenera and brown algae – Fucus vesiculosus and green algae for example: Chlorella vulgaris. They are used in cosmetology, pharmacy, food industry, agriculture and environmental protection. Hence, getting to know the current state of the market and knowledge of the preparations containing algae and the promotion of knowledge about their effectiveness is expedient to influence effectively on the prevention of civilization diseases. Conducting a survey on knowledge of the preparations of algae, efficiency and preventive properties may allow to know the current state of knowledge in Poland, about the development of effective promotion in order to use of them. The aim of the study was to assess the knowledge and the possibility of using supplements and food additives containing algae and assessment of the effectiveness of activities in the first reinforcement and anti-aging preparations containing algae in the studied groups of people. Algae due to the fact that are a source of many substances such as amino acids, proteins, minerals, vitamins, polysaccharides, lipids, and polyamides, which are necessary for the proper functioning of the human body, have been used in various industries.

12

The role of lines and corners of geometric figures in recognition performance

100%

Shevelev I. A., Kamenkovich V. m., Sharaev G. A.

Acta Neurobiologiae Experimentalis

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2003

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vol. 63

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issue 4

361-368

EN

A relative role of lines and corners of images of outline geometric figures in recognition performance was studied psychophysically. Probability of correct response to the shape of the whole figure (control) and figures with lines or corners masked to a different extent was compared. Increase in the extent of masking resulted in a drop of recognition performance that was significantly lower for figures without corners, than for figures without part of their lines. The whole 3D figures were recognized better than 2D ones, whereas the opposite relations were observed under conditions of masking. Significant gender difference in a recognition performance was found: men recognize entire and partly masked figures better than women. Possible mechanisms of relatively better recognition of figures with corners than with lines are discussed in connection with finding of high sensitivity of many neurons in the primary visual cortex to line crossing and branching.

13

Ethnobotanical Survey of Folklore medicinal Plants from Dimapur District of Nagaland, India

100%

Rajaganesh K., Sumedha N. C., Basha S. A., Venulu v., Murali M.

World News of Natural Sciences

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2021

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vol. 39

22-29

EN

An Ethnobotanical (EBot) survey was undertaken to collect information from local people about the use of medicinal plants (MPs) in Dimapur district of Nagaland, and local people use certain folklore medicinal plants for the treatment of various ailments and diseases. The aboriginal Naga tribes have a rich knowledge, based on their natural resources, of indigenous folk medicine. Their beliefs and folk practices are based on past experience with various diseases and their cures. The significant of the study is that certain plants are believed to have multi-chemical properties in healing and curing as it differs from other neighbouring communities. This paper highlights the ethnomedicinal (EMed) uses of 63 different species of plants used by the different tribe.

14

Tricholoma equestre species as a source of indole compounds and zinc released into artificial digestive juices

100%

KAŁA K., SUŁKOWSKA-ZIAJA K., ROJOWSKI J., OPOKA W., MUSZYŃSKA B.

Medicina Internacia Revuo

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2016

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vol. 27

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issue 106

35-39

EN

The research goals of presented work consisted of determination of zinc and indole compounds that are released into artificial digestive juices from Tricholoma equestre species. During the experiment freeze-dried samples of wild growing fruiting bodies and mycelia from in vitro cultures from liquid Oddoux medium were extracted to artificial digestive juices (saliva, gastric juice and intestinal juice). In the next step the determination of examined compounds was done by RP-HPLC for indole compounds and DP ASV for zinc. Furthermore it was decided to check weather this species has any beneficial properties for health. The extraction of researched material in conditions imitating human digestive tract allows determination of true amounts of elements released to artificial digestive juices and their beneficial influence (a specially designed and constructed apparatus Gastroel-2014 was applied). The indole compound with the highest quantity was 5-hydroxy-L-tryptophan, both in fruiting bodies and in biomass from in vitro cultures of T. equestre (up to 352.47 mg/100 g d.w.). Serotonin and L-tryptophan was determined in all analysed samples, but their amounts were significantly lower than the ones found for 5-hydroxy-L-tryptophan. The amounts of zinc on the other hand showed that the biggest concentration of zinc can be obtained for fruiting bodies and biomass from in vitro cultures to both artificial saliva and gastric juice after 120 minutes of digestion (6.83 14.4 mg/100 g d.w. retrospectively) in conditions that imitate human digestive track.

15

Anatomical assessment of the fibers in the trunk of Alstonia boonei for some derived indexes

100%

Otoide J. E., Tedela P. O., Akerele O. D., Adetunji D. O.

World News of Natural Sciences

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2018

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vol. 20

54-61

EN

Derived anatomical indexes such as Runkel’s ratio, Flexibility coefficient and Felting power / Slenderness ratio of the fibers in the trunk of Alstonia boonei were assessed using standard procedures and formulas. Significant differences (P≤ 0.05) existed in the Runkel’s ratio and Flexibility coefficient of the fibers along the axial position of the trunk, whereas, along the radial position, the differences were not significant (P≤0.05). Conversely, the Felting power/ Slenderness ratio of the fibers along the axial and radial positions of the trunk were not significantly different (P≤0.05) from one another. Totals of 0.65 ± 1.33, 68.32 ± 15.39 and 39.89 ± 15.41 were the Runkel’s ratio, Flexibility coefficient and Felting power/Slenderness ratio of the fibers. In view of the results obtained in the present assessment, assertions confirming the suitability of the trunk of Alstonia boonei as alternative sources of raw material for pulp and paper production were made.

16

Determination of Total Phenolic Content and Some Selected Metals in Extracts of Moringa oleifera, Cassia tora, Ocimum gratissimum, Vernonia baldwinii and Telfairia occidentalis Plant Leaves

100%

Louis H., Maitera O. N., Boro G., Barminas J. T.

World News of Natural Sciences

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2017

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vol. 11

11-18

EN

The main objective of this research is to determine the content of metals (Ca, Cu, Fe, Mg and Zn) and total phenols in different plant extracts of Moringa oleifera, Cassia tora, Ocimum gratissimum, Vernonia baldwinii and Telfairia occidentalis. Content were determined using Atomic Absorption Spectroscopy. The result indicate that Moringa oleifera plant extracts range from 0.25 ±0.00 to 6.13 ±0.30 mg/kg, Cassia tora plant extracts - 0.17 ±0.03 to 7.48 ±0.06 mg/kg, Ocimum gratissimum plant extracts - 0.18 ±0.00 to 5.43 ±0.12 mg/kg, Vernonia baldwinii and Telfairia occidentalis plant extracts - 0.21 ±0.03 to 7.86 ±0.12 mg/kg and 0.17 ±0.00 to 4.52 ±0.06 mg/kg, respectively. The results also revealed a lower abundance of heavy metals. The total phenolic content was determined using the modified Folin-Ciocalteu method. Herein, the phenolic content in Moringa oleifera was 8.50 ±1.23 mg Garlic Acid Equivalent g-1 (mg GAE g-1), Cassia tora - 30.00 ±0.00 mg GAE g-1, Ocimum gratissimum - 45.00 ±1.41 mg GAE g-1 , Vernonia baldwinii - 49.00 ±1.14 mg GAE g-1 and Telfairia occidentalis - 46.6 7 ±0.27 mg GAE g-1. We found the lowest total phenol content in Moringa oleifera. This also possessed high chelating activity. In contrast, Vernonia baldwinii contained the highest total phenol content, but had low chelating activity. The plant extracts with high levels of phenolic compounds exhibited good antioxidant activity.

17

Influence of Rhizophagus irregularis Inoculation on Salt Tolerance in Cucurbita maxima Duch.

100%

Okon O. G., Okon I. E.

World News of Natural Sciences

|

2018

|

vol. 19

108-117

EN

The influence of mycorrhizal fungi (Rhizophagus irregularis) on salt tolerance of Cucurbita maxima grown in saline soil was investigated in a pot experiment. The experiment was laid out in a completely randomized design, with treatments replicated thrice. Accordingly, soil salinity significantly (p=0.05) reduced total photosynthetic pigments from 58.06 to 38.06 mg/kg. Mineral contents, biomass yield, AMF colonization were also significantly (p=0.05) reduced. In contrast, mycorrhizal dependency was significantly (p=0.05) increased in saline soil plants (from 26.91% to 66.45%). Furthermore, inoculation with R. irregularis significantly (p=0.05) increased total photosynthetic pigments from 58.06 to 62.06 mg/kg; N from 4.88 to 5.47%; P 860.40 to 896.22 mg/kg; K 4430.00 to 4630.00 mg/kg; Mg 558.99 to 592.10 mg/kg and Ca 2810.00 to 3151.00 mg/kg; biomass yield; leaf dry weight from 0.06 to 0.14g; vine dry weight 3.68 to 5.09g; roots dry weight 0.32 to 0.74 and total dry weight 4.06 to 5.97g, R. irregularis colonization (from 33.77 to 58.44%) and mycorrhizal dependency in C. maxima was evident in both saline and non-saline soil treatments. The results of this work shows that R. irregularis can enhance the ability of C. maxima to resist salt stress - possibly through some morphological/ physiological changes, as well as improved vigour, probably via the extensive network of the mycorrhizal roots. This last is considered to be one of several mechanisms that magnify the salt tolerance of host plants through increased nutrient acquisition (N, P, K, Mg and Ca) and water uptake. Inoculation with appropriate AMF can, therefore, be used to increase the productivity of C. maxima in saline soils.

18

Effect of unilateral ibotenate lesions of the ventral tegmental area on cortical and hippocampal EEG in freely behaving rats

100%

Jurkowlaniec E., Tokarski J., Trojniar W.

Acta Neurobiologiae Experimentalis

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2003

|

vol. 63

|

issue 4

369-375

EN

It was found previously that unilateral destruction of the ventral tegmental area (VTA) facilitated behavioral responses (exploration, eating) induced by electrical stimulation of the contralateral VTA. The same effect occurred after unilateral injections of pharmacological agents, which led to a decrease in dopaminergic transmission in the VTA. While trying to explain the mechanism behind this 'contralateral facilitation effect' in the present experiment we examined whether augmentation of function of the contralateral hemisphere would be reflected in cortical and hippocampal EEG changes in conscious rats. Unilateral, cytotoxic lesion of the VTA caused a bilateral decrease in neocortical and hippocampal EEG power during both exploratory sniffing and eating. Depression involved all the frequency bands in the prefrontal cortex, mainly in the hemisphere contralateral to the VTA lesion. In the hippocampus the depression was slightly more intense ipsilaterally, also involving all the frequency bands although to different degrees. The results indicate that the VTA is involved in the regulation of cortical and hippocampal activity during VTA-dependent behavioral activation, and that the 'contralateral facilitation effect' is concomitant with lateralized changes in EEG activity.

19

Effect of Pre-chilling and Storage Temperature on Seed Germination of Solanum macrocarpon L. (African Eggplant)

100%

Ogunrotimi D. G., Kayode J.

World News of Natural Sciences

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2018

|

vol. 20

121-128

EN

This study examined the effects of storage temperature and pre-chilling on the germination of the seeds of Solanum macrocarpon – which according to literature has a seed viability of 63.33%. In our study, the seeds were sown in dry Petri dishes and placed in the refrigerator set at 4 °C for 1, 3, 5, 7 and 10 days. Another set of seeds was placed in incubators set at 25, 35 and 45 °C for 40 days before the germination experiment was carried out on a laboratory workbench. Results from the study revealed that while storage temperature had a significant effect on that the germination of seeds of this plant, pre-chilling of seeds and incubator treatments generally reduced seed germination. Thus seed germination in this plant is temperature dependent.

20

Evaluation of new MMN parameters in schizophrenia

100%

Korostenskaja M., Dapsys K., Maciulis V., Ruksenas O.

Acta Neurobiologiae Experimentalis

|

2003

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vol. 63

|

issue 4

383-388

EN

ERPs could be helpful in the objectification of many psychological measures. In the last few decades one of the most commonly used ERPs has been the mismatch negativity (MMN) potential. It may be used to detect cognitive dysfunction in patients suffering from schizophrenia, dementia, depression, and can also be successfully applied in treatment monitoring. Nevertheless, changes of MMN parameters (prolongation of latency or reduction of amplitude) are not sufficiently specific to help to diagnose particular diseases. In this study we looked for more strict and specific MMN characteristics selective for schizophrenia. Fifteen healthy human subjects and twelve suffering from schizophrenia spectrum disorders were studied. Two new parameters were considered: the speed of ascending part of MMN slope (SAS) and the half area of the MMN wave. These two measures could differentiate the early stages of cognitive processing disturbances in schizophrenia spectrum disorders.

Refine search results

Therapeutic strategies for Alzheimer's disease based on new molecular mechanisms

ACCUMULATION OF P-COUMARIC ACID AND OTHER BIOACTIVE PHENOLIC ACIDS IN IN VITRO CULTURE OF RUTA GRAVEOLENS SSP. DIVARICATA (TENORE) GAMS.

Analysis of the content of phenolic compounds in in vitro culture of some edible mushrooms (Basidiomycota)

Thyroid function in patients with Alzheimer's disease treated with cholinesterase inhibitors

List of ornamental and useful plants cultivated on Huahine Island, French Polynesia. Part 1

Review on pharmacological and biological properties of Acalypha fruticosa Forssk

Survey of benefits and constraints of urban trees in Kaduna Metropolis

Natural products in dentistry

Zinc determination in extracts from bacopa monnieri shoot cultures into simulated gastric fluids.

In Vitro Micropropagation of Vernonia cinerea (L.) Less. - An important medicinal herb

Algae preparations as a source of beneficial healthy substances

The role of lines and corners of geometric figures in recognition performance

Ethnobotanical Survey of Folklore medicinal Plants from Dimapur District of Nagaland, India

Tricholoma equestre species as a source of indole compounds and zinc released into artificial digestive juices

Anatomical assessment of the fibers in the trunk of Alstonia boonei for some derived indexes

Determination of Total Phenolic Content and Some Selected Metals in Extracts of Moringa oleifera, Cassia tora, Ocimum gratissimum, Vernonia baldwinii and Telfairia occidentalis Plant Leaves

Influence of Rhizophagus irregularis Inoculation on Salt Tolerance in Cucurbita maxima Duch.

Effect of unilateral ibotenate lesions of the ventral tegmental area on cortical and hippocampal EEG in freely behaving rats

Effect of Pre-chilling and Storage Temperature on Seed Germination of Solanum macrocarpon L. (African Eggplant)

Evaluation of new MMN parameters in schizophrenia