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1

Resistance Training in Type 2 Diabetic Patients Improves Uric Acid Levels

100%

R. Sousa M. S. S., Saavedra F. J. F., Neto G. R., Novaes G. S., Souza A. C. R., Salerno V. P., Novaes J. S.

Journal of Human Kinetics

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2014

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vol. 43

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issue 1

17-24

EN

Resistance training (RT) can provide several benefits for individuals with Type 2 diabetes. The aim of this study was to investigate the effects of resistance training on the strength levels and uric acid (UA) concentration in individuals with Type 2 diabetes. The study included 68 patients (57.7±9.0 years) that participated in an organized program of RT for 12 weeks. The volunteers were divided into two groups: an experimental group (EG; n=34) that performed the resistance training program consisting of seven exercises executed in an alternating order based on segments; and a control group (CG; n=34) that maintained their normal daily life activities. Muscle strength and uric acid were measured both pre- and post-experiment. The results showed a significant increase in strength of the subjects in the EG for all exercises included in the study (p<0.001). Comparing the strength levels of the post-test, intergroup differences were found in supine sitting (p<0.001), leg extension (p<0.001), shoulder press (p<0.001), leg curl (p=0.001), seated row (p<0.001), leg press (p=0.001) and high pulley (p<0.001). The measured uric acid was significantly increased in both experimental and control groups (p<0.001 and p=0.001, respectively). The intergroup comparison showed a significant increase for the EG (p=0.024). We conclude that the training program was effective for strength gains despite an increase in uric acid in Type 2 diabetics.

2

Elevated high sensitivity C-reactive protein and uric acid levels in coronary artery ectasia

100%

Demir Ş., Karakoyun G., Kanadasi M.

Acta Biochimica Polonica

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2014

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vol. 61

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issue 4

687-691

EN

Aim: The aim of this study is to examine uric asid (UA) and high sensitive C-Reactive protein (Hs-CRP) levels in patients with coronary artery ectasia (CAE). Materials and Methods: Ninety-eight patients with isolated CAE (mean age 57.5±10.3), (group-I), 110 patients with CAD but without CAE (mean age 56.3±10.7), (group-II), and 105 patients with normal coronary angiographies (mean age 58.1±10.8), (group-III) were included in the study. Blood samples of all individual were taken after coronary angiography from an antecubital vein, the patients uric acid and Hs-CRP levels were assessed. The severity of ectasia was evaluated and categorized according to Markis. Results: A significant difference was not seen in serum uric acid and Hs-CRP levels between CAE and CAD groups. However, relative to the control group, uric acid and Hs-CRP levels in CAE and CAD groups were higher to a significant degree (p=0.001, p<0.001, respectively), (p<0.001, p<0.001, respectively). The statistical significant was detected between subgroups type I and type IV, Hs-CRP and UA were statistically high in subgroup type I. (p=0.012, p=0.033, respectively) In multiple regression analysis, CAE and CAD were independently associated with UA (β=0.76; p<0.001, β=0.68; p<0.001, respectively) and Hs-CRP (β=0.66; p<0.01, β=0.62; p<0.01, respectively) along with diabetes mellitus (β=0.61; p=0.039, β=0.94; p=0.028, respectively). Conclusion: In conclusion, the blood uric acid and Hs-CRP values in our study have been observed to be higher in the individuals with coronary arteri ectasia in comparison to normal individuals, and the increase in these values were found to be parallel to the extent of the ectasia.

3

Cytostatic therapy and blood antioxidants/prooxidants balance in acute myeloblastic leukemia patients

88%

Gerova D., Gerov V., Yankova T., Gercheva L., Ivanova D.

Open Medicine

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2006

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vol. 1

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issue 1

35-45

EN

To analyze the effects of conventional polychemotherapy of acute myeloblastic leukemia (AML) patients on the prooxidants/antioxidants balance in plasma total antioxidant status (TAS) and a single plasma antioxidant - uric acid (UA) were measured. Lipid peroxidation was assessed by malonedialdehyde (MDA) content. Total serum iron was monitored as a potential source of nontransferrin-bound iron with a role in initiation of oxidative burst. A group of patients in the acute phase of AML (group A) and a group of patients in complete remission of AML (group B) were studied. A strong correlation between UA values and TAS (r = 0.8 for group A, r = 0.9 for group B) was revealed in the course of the treatment. Strong negative correlation (r = −0.9) between TAS and MDA was shown for both groups. Total iron significantly increased in the course of chemotherapy. We have established that polychemotherapy leads to the consumption of antioxidants and increased lipid peroxidation in AML patients. An appropriate supplementation with antioxidants at the end of the polychemotherapy treatment could be considered.

4

Uric acid in the surface waters of Spitsbergen and its role in the dissolution processes which affect carbonate rocks

75%

Burzyk M., Pulina M., Sajewicz M., Zjawiony I., Burzyk M., Pulina M., Sajewicz M., Zjawiony I.

Polish Polar Research

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2006

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vol. 27

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issue 4

5

Purine metabolism in the light of aerobic and anaerobic capacity of female boxers

75%

Domaszewska K., Szewczyk P., Kryściak J., Michalak E., Podgórski T.

Central European Journal of Sport Sciences and Medicine

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2020

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vol. 30

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issue 2

97-106

EN

The aim of the work was to assess the intensity of purine nucleotide degradation during maximum physical exercise. 5 elite female boxers were the subject of the study. Each of them underwent two exercise stress tests in order to evaluate the level of V̊O2peak and the level of anaerobic capacity during a Wingate test. The study involved collecting capillary and venous blood samples at rest and after the exercise test to determine the Acid-Base Balance (ABB), concentration of lactic acid (LA) and purine metabolism nucleotides. The average value of V̊O2peak was 40.92 (SD = 4.087) ml/kg/min, the average anaerobic capacity Ppeak was 7.57 (SD = 0.380) Watt/kg. The workload resulted in significant changes in the level of ABB and LA after both of the exercise stress tests (p < 0.001). Concentrations of hypoxanthine (Hx), xanthine (X) and uric acid (UA) in the blood increased significantly after the Wingate test (p < 0.05). The level of plasma purine nucleotides at rest and after standard exercise may be a useful tool for monitoring the adaptation of energetic processes in different training phases and support the overload diagnosis.

6

Ferric reducing ability of plasma and assessment of selected plasma antioxidantsin adults with celiac disease

75%

Piątek-Guziewicz A., Mach T., Zagrodzki P., Paśko P., Krośniak M., Zwolińska-Wcisło M.

Folia Medica Cracoviensia

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2017

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vol. 57

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issue 4

7

Determination of adenine nucleotides and their metabolites in human saliva.

75%

Kochańska B., Smoleński R. T., Knap N.

Acta Biochimica Polonica

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2000

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vol. 47

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issue 3

877-879

EN

The profile and normal concentrations of nucleotide metabolites in human saliva and reproducibility of these determinations were analyzed. Samples of human saliva collected from healthy individuals at weekly intervals, were deproteinized and analysed for the content of adenine nucleotides and their metabolites by reversed-phase HPLC. Initial ATP, hypoxanthine and uric acid concentrations were 0.52 ± 0.15 μM, 1.91 ± 0.37 μM and 184 ± 22 μM respectively. A substantial individual variation persisted within 3 weeks of sampling excepted hypoxanthine which showed some unrelated variations. Determination of nucleotides and their catabolites in saliva due to its simplicity and reproducibility, may be of clinical value in diagnosis of local or systemic disorders.

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Resistance Training in Type 2 Diabetic Patients Improves Uric Acid Levels

Elevated high sensitivity C-reactive protein and uric acid levels in coronary artery ectasia

Cytostatic therapy and blood antioxidants/prooxidants balance in acute myeloblastic leukemia patients

Uric acid in the surface waters of Spitsbergen and its role in the dissolution processes which affect carbonate rocks

Purine metabolism in the light of aerobic and anaerobic capacity of female boxers

Ferric reducing ability of plasma and assessment of selected plasma antioxidantsin adults with celiac disease

Determination of adenine nucleotides and their metabolites in human saliva.