Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl
Preferences help
Polish version English version Language
enabled [disable] Abstract
Number of results

Results found: 3

Number of results on page
first rewind previous Page / 1 next fast forward last

Search results

Search:
in the keywords:  tablets
help Sort By:

help Limit search:
first rewind previous Page / 1 next fast forward last
1
Content available remote

Review on analgesic effect of co-administrated ibuprofen and caffeine

100%
Polski A., Kasperek R., Sobotka-Polska K., Poleszak E.
Current Issues in Pharmacy and Medical Sciences
|
2014
|
vol. 27
|
issue 1
10-13
EN
Pain is a symptom of many diseases and significantly affects the quality of life, so researchers are constantly seeking new substances to be used as analgesics. Other, easier way is to combine already known drugs which cause synergistic effects greater than additive, so that probability of drug-specific side effects can be reduced. Researchers showed that caffeine can be an effective analgesic adjuvant enhancing antinociceptive effect of ibuprofen in animals and humans. By using modern drug technology methods tablets containing well-soluble ibuprofen salt and caffeine can be easily prepared. Thanks to that combination, the therapeutic dose of ibuprofen can be lowered and the side effects may be reduced.
2
Content available remote

Comparative validation of HPLC, densitometric and videodensitometric determination of lamotrigine in pharmaceutical

100%
Paw B.
Current Issues in Pharmacy and Medical Sciences
|
2014
|
vol. 27
|
issue 4
258-262
EN
Simple, sensitive, precise and accurate HPLC, densitometric and videodensitometric methods for determination of lamotrigine in tablet forms were developed and validated. The HPLC method was carried out using a Symmetry C8 column and a mobile phase acetonitrile-phosphate buffer pH 2.80 (25:75, v/v), with a flow rate of 1 mL/min, and UV detection at 210 nm. Ethosuximide was used as the internal standard. Densitometric and videodensitometric analysis was performed on silica gel 60 F254 plates, in horizontal chambers, with methanol-chloroform-ammonia (25%) 1.5:7.5:1, (v/v) as mobile phase. Densitometric detection was performed at 225 nm and at 315 nm, and videodeoscanning at 254 nm. Calibration plots were constructed in the range 0.5-10 μg/spot, with good correlation coefficients r > 0.99 for both methods. The precision and accuracy of all elaborated methods were compared. Finally, the developed methods were applied for the quality control of lamotrigine tablets.
3
Publication available in full text mode
Content available

THE EXCIPIENTS USED IN THE NON-COATED TABLETS - A REVIEW

100%
POLSKI A., IWANIAK K., NALEŚNIAK M., POLESZAK E.
Medicina Internacia Revuo
|
2014
|
vol. 26
|
issue 102
10-18
EN
In modern drug technology excipients fulfill many important roles: antiadherents, binders, disintegrants, fillers, flavours, lubricants, etc. They can modify many properties of tablets including disintegration time, substance release place (stomach, intestine) and time (fast or slow release, non-modified), improvement of taste and flavor, etc. There are many scientific reports that can help choose suitable excipients to produce tablets that have desired properties. That paper was created to arrange knowledge about them.
first rewind previous Page / 1 next fast forward last
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.