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One of the most commonly affected organ systems by SARS-CoV-2 virus is the respiratory system. Major challenge with coronavirus disease is managing the pulmonary complications. Role of non-invasive ventilation in patients of coronavirus disease 2019 (COVID 19) has been questioned in spite of evidence showing its use in acute hypoxemic respiratory failure. Patient selection is very important when using non-invasive ventilation for management of respiratory failure due to COVID 19. Here we report a case of COVID 19 with respiratory failure that was managed successfully with prolonged use of non-invasive ventilation.
EN
In this review, the classification of respiratory muscle fatigue from the perspective of its origin is presented. The fatigue is classified as central or peripheral, and the latter further subdivided into high- and low-frequency fatigue. However, muscle fatigue is a complex process and all three types of fatigue probably occur simultaneously in the overloaded respiratory muscles. The relative importance of each type depends on the duration of respiratory loading and other physiological variables. However, central and high-frequency fatigue resolve rapidly once muscle overload is removed, whereas low-frequency fatigue persists over long time.
EN
INTRODUCTION: For many months now, the entire world experiences effects of the COVID-19 pandemic, and current data indicate that this condition will continue even longer. About 5% of patients who become infected with the SARSCoV-2 coronavirus may develop a critical form of severe respiratory failure, due to which they will undergo intubation and mechanical ventilation. Prolonged mechanical ventilation will be an indication for an open tracheostomy, burdened with an increased production of aerosol containing virus particles and an increased risk of transmitting the highly contagious pathogen to medical personnel. In this situation, surgical departments with a limited number of operating theaters may be dedicated only to COVID-19 patients. Their use for other procedures will be significantly reduced or even impossible to prevent transmission of infections and exposure to other people. Taking into account the well-being of patients and staff and limiting the transmission of the virus to other departments, other safe solutions are being sought to perform a tracheostomy. An alternative procedure may be to perform a tracheostomy directly at the bedside (point-of-care) of a patient hospitalized in an intensive care unit (ICU). PURPOSE: The purpose of the study is to present an effective performance of safe, open tracheostomy in the ICU. METHODS: The bedside tracheotomy as an alternative to the procedure performed in the setting of an operating theater has been presented. A case study was based on the analysis of the procedure performed in a 42-year-old patient who was installed an open tracheotomy tube on the twenty-ninth day of intubation. CONCLUSIONS: In order to limit the transmission of the SARS-CoV-2 coronavirus outside the intensive care unit, it is recommended to perform a tracheotomy in ICU, in patients requiring mechanical ventilation, as the method is effective and safe.
EN
COVID pandemic has been a cause of extensive morbidity and mortality worldwide. Patients with severe COVID have been observed to suffer from remnant lung damage, fibrosis and oxygen dependency. These patients have still an unpredictable course and outcome. The outcome of these patients is not clearly defined yet. The signs and symptoms in such patients persisting even 4 weeks after acute COVID-19 has been recently named as "Long COVID". In the present case series, we present the course and outcome of two such ‘Long COVID’ patients who presented with severe hypoxemic respiratory failure. These patients were managed with a prolonged application of Non-invasive ventilation with high flow oxygen and alongwith glycaemic control, steroids and antibiotics. The patients showed tremendous response to the treatment and could be weaned from NIV after about three weeks of therapy. These cases demonstrate the utility of NIV, even in severe hypoxemic respiratory failure, in Long COVID.
PL
Pandemia COVID była przyczyną rozległej zachorowalności i śmiertelności na całym świecie. Zaobserwowano, że pacjenci z ciężkim COVID cierpią z powodu resztkowego uszkodzenia płuc, zwłóknienia i uzależnienia od tlenu. Ci pacjenci nadal mają nieprzewidywalny przebieg choroby i jej zakończenie. Wynik końcowy tych pacjentów nie jest jeszcze jasno określony. Oznaki i objawy u takich pacjentów utrzymują się nawet 4 tygodnie po ostrym COVID-19, co zostało niedawno nazwane "Długim COVID". W niniejszej serii przypadków przedstawiamy przebieg i wyniki dwóch pacjentów z "długim COVID", u których wystąpiła ciężka hipoksemiczna niewydolność oddechowa. Pacjenci ci byli leczeni z przedłużonym zastosowaniem wentylacji nieinwazyjnej z wysokim przepływem tlenu, wraz z kontrolą glikemii, sterydami i antybiotykami. Pacjenci wykazali się niesamowitą odpowiedzią na leczenie i można było odstawić NIV po około trzech tygodniach terapii. Te przypadki pokazują użyteczność NIV, nawet w ciężkiej hipoksemicznej niewydolności oddechowej, w przewlekłym COVID.
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