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EN
Gastroesophageal reflux disease (GERD) constitutes a significant health problem in societies of high socioeconomic status. The notion of quality of life is broader than the definition of health and encompasses two aspects: the subjective and objective one. The tools used for the evaluation of quality of life are questionnaires.The aim of the study was the evaluation of the original quality of life questionnaire in patients with gastroesophageal reflux disease treated for 4 weeks with a single dose of omeprazole at 20 mg daily.Material and methods. The original quality of life questionnaire was formulated based on the Likert method. Four time levels of complaint persistence were introduced. The patients were asked 10 questions with earlier prepared answers marked by the respondents. Each of the questions corresponded to a certain time level of complaint persistence. The data obtained from the questionnaires were subject to statistical analysis. The studies were conducted on a group of 10,623 patients. Adequate methods were used in the statistical analysis of data from obtained answers. The significance threshold for each of the studies was p < 0.01, which means that the obtained conclusions are true with the probability of at least 99%. The majority of statistical calculations were performed with the use of STATISTICA 7.0 and Excel software.Results. Improvement of quality of life was found in all the studied aspects: physical (questions 1, 3, 4, 5, 7), functional (question 6), emotional (questions 2, 10) and social (questions 8, 9). No correlation with age or gender was found. The analysis of test correctness was conducted, revealing reliability, validity, sensitivity, appropriateness and practicality of the questionnaire.Conclusions. 1. The original quality of life questionnaire meets the requirements for the tools evaluating quality of life in gastroesophageal reflux disease. 2. The usefulness of questionnaire was confirmed in a group of 10,623 patients with gastroesophageal reflux disease in the Polish population. 3. The questionnaire equals the international tests, while its advantages are the ease of completion and high level of perception.
EN
According to the statement of the World Health Organization, the quality of life is the individual’s perception of their position in life in the context of given standards and value systems and in relation to their accomplishments, expectations and concerns. In the past twenty-five years, the role of quality of life assessment in medicine has been growing. Health-related quality of life is the self-assessment of patients with respect to the influence of a disease and treatment on the functioning in basic aspects: physical, mental, social and spiritual. The quality of life measure is a very useful tool for the assessment of the value of medical procedures. Quality of life is measured using the QALY index (quality-adjusted life years), which is the average further duration of life adjusted by the limitation of activity due to a disease or disability. Each medicinal technology, the costs of which are reimbursed from public funds, is subject to pharmacoeconomic assessment, and QALY is one of its elements. Quality of life is significant for patients but it is difficult to express in methodological categories. The basic evaluation methods include patient-reported outcomes of treatment with the use of one-dimensional analogue, numerical and verbal scales or multidimensional questionnaires.
PL
Zgodnie ze stanowiskiem Światowej Organizacji Zdrowia jakością życia nazywamy indywidualny odbiór przez człowieka jego pozycji życiowej w kontekście określonych standardów i systemu wartości oraz w odniesieniu do osiągnięć, oczekiwań i zainteresowań. W ostatnim ćwierćwieczu systematycznie rośnie znaczenie oceny jakości życia w medycynie. Jakość życia uwarunkowana zdrowiem to samoocena chorego odnośnie do wpływu choroby i stosowanego leczenia na funkcjonowanie w podstawowych aspektach: fizycznym, psychicznym, społecznym i duchowym. Pomiar jakości życia jest bardzo przydatnym narzędziem oceny wartości procedur medycznych. Do mierników jakości życia należy wskaźnik QALY (quality-adjusted life years), czyli przeciętne dalsze trwanie życia skorygowane o ograniczenie aktywności w wyniku choroby lub niepełnosprawności. Każda lekowa technologia medyczna, której koszty mają być refundowane z funduszy publicznych, podlega ocenie farmakoekonomicznej, a QALY to jeden z elementów tej oceny. Jakość życia jest istotna dla chorych, lecz trudna do wyrażenia w kategoriach metodologicznych. Do podstawowych metod ewaluacji należy samoocena wyników leczenia dokonywana przez chorego za pomocą jednowymiarowych skal analogowych, numerycznych i słownych czy też wielowymiarowych kwestionariuszy.
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