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Effect of pesticide residue in food crops on man and his environment

100%
Obunadike C. V., Yakubu Y. Y., Abdulrazaq O. O., Ogunsanmi A. O., Muhammad Z., Adio W. S., Lawal I. A., Adisa A. S.
World News of Natural Sciences
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2022
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vol. 44
192-214
EN
The use of pesticides has been a catalyst that improves crop quality and yield. It can be designed using conventional or modern technologies depending on the type of pesticides being used. It is used to prevent organisms that are considered to be harmful to crop growth and development by protecting them from pests and diseases, thus increasing food crop’s quality. There are several classifications of pesticides among which are; insecticides, fungicides, rodenticides, etc. Physicochemical and biological methods are the basic two ways of detecting pesticide poisoning. Immunoassays (biological) are the most prominent methods of detection, it requires the use of fluorescent, chemiluminescent or other detection methods to detect drugs, proteins, and some hormones. Pesticide residues are responsible for environmental pollution such as groundwater contamination, global warming and killing non-target organisms in the soil. Exposing the human body to excess pesticide residue can lead to various severe health conditions such as cancer, asthma, etc. The metabolism of pesticides in the body system undergoes two stages, namely; phase one and phase two. oxidation reactions occur in phrase one whereby pesticides functional groups are majorly synthesized by Cytochrome P450 enzymes. Phase two includes the reactions of phase I substrate with glucuronic acid (C6H10O7), tetraoxosulphate(VI) acid (H2SO4), ethanoic acid (CH3COOH), etc. to form more polar compounds for easy excretion. The introduction of inexpensive biodegradable pesticides and the enforcement and implementation of pesticide control and regulation laws has helped to decrease the negative effects of pesticide residue in humans and the surroundings. Pesticide residue can be eliminated or reduced from food crops by practicing organic farming, washing, and food product processing, natural pesticide application, and rational use of pesticides. It is highly recommended to follow the prescription of pesticides used to avoid its toxicity in the biological systems.
2
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Recurrent hypertrophic laryngeal lesions in a patient with a history of pesticide exposure – a case report

88%
Kloc M., Krawczyk P., Rzepakowska A., Niemczyk K.
Polski Przegląd Otorynolaryngologiczny
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2020
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vol. 9(1)
39-44
EN
Chronic irritation of the laryngeal mucosa by external factors can lead to the development of dysphonia: hoarseness, change of the voice tone or weakening of its strength. Patients who additionally report alarming symptoms, such as dyspnea, dysphagia, or odynophagia require urgent diagnosis and treatment. Long-term exposure to irritants may lead to the development of numerous recurrent hypertrophic laryngeal lesions requiring continuous otorhinolaryngological care and multiple surgical procedures, as it was in the presented case.
3
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The effect of DDE and dieldrin and their parental substances (DDT and aldrin) on PGE2 and PGF2α release from bovine endometrial explants collected during 120 to 180 days of the gestational period

75%
Mlynarczuk J., Wrobel M. H., Dobrzyn K., Mlynarczuk J., Wrobel M. H., Dobrzyn K.
Polish Journal of Veterinary Sciences
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2021
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vol. 24
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issue 1
4
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Influence of pesticides on the biological activity of light chestnut soils in South-East Kazakhstan

75%
Tukenova Z., Mustafayev M., Alimzhanova M., Akylbekova T., Ashimuly K., Tukenova Z., Mustafayev M., Alimzhanova M., Akylbekova T., Ashimuly K.
Journal of Water and Land Development
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2021
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issue 48
5
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Wybrane ksenoestrogeny i ich wpływ na zdrowie człowieka

63%
Forma E., Szymczak A., Krześlak A.
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vol. 40
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issue 1
79-97
EN
Xenoestrogens are typically identified as compounds that can interact with estrogen receptors and thus, can act as agonists or antagonists of endogenous hormones. Exogenous estrogens are highly heterogeneous in structure and include metals and synthetic organic compounds such as pesticides, plastics, as well as natural plant-derived xenoestrogens i.e. phytoestrogens. They originate from a wide variety of commonly used sources, including certain plastics, pesticides, fuels, cigarette smoke, cosmetic products and plants. It means that all human population may be exposed to them. Estrogens are recognized as a critical modulator of development, homeostasis in adulthood and the regulation of response to the environment. Xenoestrogens do not have identical properties to endogenous estrogens but perfectly mimic or interfere with all aspects of estrogen-mediated signaling. The increasing evidence suggests that xenoestrogens may cause adverse health effects. Some of xenoestrogens can promote tumor development through the stimulation of cell proliferation, angiogenesis and metastasis. On the other hand, phytoestrogens have been shown to exert a protective effect against the development of breast cancer.
PL
Ksenoestrogeny to egzogenne związki chemiczne mogące oddziaływać z receptorami estrogenowymi i działać jako agoniści lub antagoniści endogennych hormonów. Egzogenne estrogeny to heterogenna pod względem struktury chemicznej grupa substancji obejmująca metale, związki syntetyczne, takie jak pestycydy, składniki tworzyw sztucznych, a także naturalne substancje roślinne, tj. fitoestrogeny. Do źródeł ksenoestrogenów zalicza się m.in. niektóre tworzywa sztuczne, pestycydy, spaliny, dym tytoniowy, kosmetyki oraz roślin. Istnienie tak wielu potencjalnych źródeł ekspozycji wiąże się z powszechnym narażeniem ludzi na działanie tych związków. Endogenne estrogeny odgrywają istotną rolę na etapie rozwoju oraz w regulacji homeostazy i odpowiedzi organizmu na czynniki środowiskowe. Ksenoestrogeny nie wykazują wszystkich właściwości naturalnie występujących estrogenów, jednakże mogą one naśladować ich działanie lub zaburzać transmisję sygnału z udziałem estrogenów. Wyniki wielu badań sugerują negatywny wpływ ksenoestrogenów na zdrowie człowieka. Niektóre ksenoestrogeny mogą powodować rozwój nowotworów poprzez stymulację proliferacji komórek, angiogenezy i przerzutowania. Z drugiej jednak strony, fitoestrogeny mogą hamować rozwój raka piersi.
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